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Anti-HIV reverse transcriptase plant polyphenolic natural products with in silico inhibitory properties on seven non-structural proteins vital in SARS-CoV-2 pathogenesis
BACKGROUND: Accessing COVID-19 vaccines is a challenge despite successful clinical trials. This burdens the COVID-19 treatment gap, thereby requiring accelerated discovery of anti-SARS-CoV-2 agents. This study explored the potential of anti-HIV reverse transcriptase (RT) phytochemicals as inhibitors...
Autores principales: | de Leon, Von Novi O., Manzano, Joe Anthony H., Pilapil, Delfin Yñigo H., Fernandez, Rey Arturo T., Ching, James Kyle Anthony R., Quimque, Mark Tristan J., Agbay, Jay Carl M., Notarte, Kin Israel R., Macabeo, Allan Patrick G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284420/ https://www.ncbi.nlm.nih.gov/pubmed/34272647 http://dx.doi.org/10.1186/s43141-021-00206-2 |
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