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Anti-HIV reverse transcriptase plant polyphenolic natural products with in silico inhibitory properties on seven non-structural proteins vital in SARS-CoV-2 pathogenesis

BACKGROUND: Accessing COVID-19 vaccines is a challenge despite successful clinical trials. This burdens the COVID-19 treatment gap, thereby requiring accelerated discovery of anti-SARS-CoV-2 agents. This study explored the potential of anti-HIV reverse transcriptase (RT) phytochemicals as inhibitors...

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Detalles Bibliográficos
Autores principales: de Leon, Von Novi O., Manzano, Joe Anthony H., Pilapil, Delfin Yñigo H., Fernandez, Rey Arturo T., Ching, James Kyle Anthony R., Quimque, Mark Tristan J., Agbay, Jay Carl M., Notarte, Kin Israel R., Macabeo, Allan Patrick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284420/
https://www.ncbi.nlm.nih.gov/pubmed/34272647
http://dx.doi.org/10.1186/s43141-021-00206-2

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