Toward New Transmission-Blocking Combination Therapies: Pharmacokinetics of 10-Amino-Artemisinins and 11-Aza-Artemisinin and Comparison with Dihydroartemisinin and Artemether

As artemisinin combination therapies (ACTs) are compromised by resistance, we are evaluating triple combination therapies (TACTs) comprising an amino-artemisinin, a redox drug, and a third drug with a different mode of action. Thus, here we briefly review efficacy data on artemisone, artemiside, oth...

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Detalles Bibliográficos
Autores principales: Watson, Daniel J., Laing, Lizahn, Gibhard, Liezl, Wong, Ho Ning, Haynes, Richard K., Wiesner, Lubbe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284440/
https://www.ncbi.nlm.nih.gov/pubmed/34097488
http://dx.doi.org/10.1128/AAC.00990-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284440/
https://www.ncbi.nlm.nih.gov/pubmed/34097488
http://dx.doi.org/10.1128/AAC.00990-21

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