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Chinese Herbal Medicine for Treating Epilepsy

Chinese herbal medicine has a long history of use for treating epilepsy. Because of the side effects of Western antiepileptic therapy and the quest for more accessible treatment, complementary and alternative medicines have become popular. Traditional Chinese medical diet therapy appears to be safe...

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Detalles Bibliográficos
Autores principales: Lin, Chia-Hui, Hsieh, Ching-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284486/
https://www.ncbi.nlm.nih.gov/pubmed/34276290
http://dx.doi.org/10.3389/fnins.2021.682821
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author Lin, Chia-Hui
Hsieh, Ching-Liang
author_facet Lin, Chia-Hui
Hsieh, Ching-Liang
author_sort Lin, Chia-Hui
collection PubMed
description Chinese herbal medicine has a long history of use for treating epilepsy. Because of the side effects of Western antiepileptic therapy and the quest for more accessible treatment, complementary and alternative medicines have become popular. Traditional Chinese medical diet therapy appears to be safe and effective. We searched PubMed and the Cochrane Library through November 2020 for the use of traditional Chinese medicine in clinical settings, including plants, fungi, and animals. Combinations of keywords included “epilepsy,” “seizure,” “antiepileptic,” “anticonvulsive,” “Chinese herbal medicine,” “Chinese herb,” and each of the Latin names, English names, and scientific names of herbs. We also summarized the sources and functions of these herbs in Chinese medicine. Different herbs can be combined to increase antiepileptic effects through various mechanisms, including anti-inflammation, antioxidation, GABAergic effect enhancement, modulation of NMDA channels and sodium channel, and neuroprotection. Despite reports of their anticonvulsive effects, adequate experimental evidence and randomized controlled clinical trials are required to confirm their antiepileptic effects.
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spelling pubmed-82844862021-07-17 Chinese Herbal Medicine for Treating Epilepsy Lin, Chia-Hui Hsieh, Ching-Liang Front Neurosci Neuroscience Chinese herbal medicine has a long history of use for treating epilepsy. Because of the side effects of Western antiepileptic therapy and the quest for more accessible treatment, complementary and alternative medicines have become popular. Traditional Chinese medical diet therapy appears to be safe and effective. We searched PubMed and the Cochrane Library through November 2020 for the use of traditional Chinese medicine in clinical settings, including plants, fungi, and animals. Combinations of keywords included “epilepsy,” “seizure,” “antiepileptic,” “anticonvulsive,” “Chinese herbal medicine,” “Chinese herb,” and each of the Latin names, English names, and scientific names of herbs. We also summarized the sources and functions of these herbs in Chinese medicine. Different herbs can be combined to increase antiepileptic effects through various mechanisms, including anti-inflammation, antioxidation, GABAergic effect enhancement, modulation of NMDA channels and sodium channel, and neuroprotection. Despite reports of their anticonvulsive effects, adequate experimental evidence and randomized controlled clinical trials are required to confirm their antiepileptic effects. Frontiers Media S.A. 2021-07-02 /pmc/articles/PMC8284486/ /pubmed/34276290 http://dx.doi.org/10.3389/fnins.2021.682821 Text en Copyright © 2021 Lin and Hsieh. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Lin, Chia-Hui
Hsieh, Ching-Liang
Chinese Herbal Medicine for Treating Epilepsy
title Chinese Herbal Medicine for Treating Epilepsy
title_full Chinese Herbal Medicine for Treating Epilepsy
title_fullStr Chinese Herbal Medicine for Treating Epilepsy
title_full_unstemmed Chinese Herbal Medicine for Treating Epilepsy
title_short Chinese Herbal Medicine for Treating Epilepsy
title_sort chinese herbal medicine for treating epilepsy
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284486/
https://www.ncbi.nlm.nih.gov/pubmed/34276290
http://dx.doi.org/10.3389/fnins.2021.682821
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