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FUNCTIONAL RECOVERY AFTER REVISION ACL RECONSTRUCTION WITH A SECOND AUTOGRAFT: A MATCHED COHORT ANALYSIS IN ADOLESCENT PATIENTS

BACKGROUND: Young patients are the highest risk demographic for ACL graft failure and revision surgery. Previous studies have shown higher rates of graft failure with the use of allograft tissue for ACL reconstruction (ACLR) in both primary and revision surgeries. However, questions remain regarding...

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Autores principales: Wilson, Benjamin R., Heyworth, Benton E., Coene, Ryan P., Sugimoto, Dai, Micheli, Lyle J., Kocher, Mininder S., Christino, Melissa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284524/
http://dx.doi.org/10.1177/2325967121S00107
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author Wilson, Benjamin R.
Heyworth, Benton E.
Coene, Ryan P.
Sugimoto, Dai
Micheli, Lyle J.
Kocher, Mininder S.
Christino, Melissa A.
author_facet Wilson, Benjamin R.
Heyworth, Benton E.
Coene, Ryan P.
Sugimoto, Dai
Micheli, Lyle J.
Kocher, Mininder S.
Christino, Melissa A.
author_sort Wilson, Benjamin R.
collection PubMed
description BACKGROUND: Young patients are the highest risk demographic for ACL graft failure and revision surgery. Previous studies have shown higher rates of graft failure with the use of allograft tissue for ACL reconstruction (ACLR) in both primary and revision surgeries. However, questions remain regarding the functional consequence of taking a second autograft from the same knee for revision ACLR. PURPOSE: The purpose of this study was to evaluate 6-month functional testing in patients who underwent revision ACLR with a second autograft from the same knee compared to matched cohorts of primary ACL patients. METHODS: We retrospectively reviewed prospectively collected data from patients aged 19 or younger who had revision ACLR with a second autograft at our institution. We excluded patients with iliotibial band autografts, two autografts from a synergistic muscle groups, or grafts from the contralateral knee. Patients with previous significant injury or surgery to the contralateral leg, and those with multiligamentous knee injuries were excluded. Patients underwent functional testing 5-8 months after revision surgery including anthropometric measures, isometric strength, Y-Balance, and hop testing. Side-to-side deficits were then compared to age, sex, and BMI matched cohorts of primary ACLR patients, with hamstring or patellar tendon autografts. Multivariate analysis of variance (MANOVA) was used, and if significance was detected, pairwise comparison was performed by Bonferroni post-hoc correction. Statistical significance of p<0.05 was applied. RESULTS: Thirty-seven adolescents underwent functional testing at 6.25±0.56 months after revision ACLR with a second autograft. These patients were matched to 62 patients who underwent primary ACLR with hamstring autograft, and 47 who underwent ACLR with patellar tendon autograft (Table 1). Revision ACLR patients showed comparable knee extension strength deficits to the patellar tendon group (-9.45±12.09% vs -8.81±13.83%, p=0.999) which were significantly greater than hamstring group (-9.45±12.09% vs -0.99±12.00%, p<0.05). Greater strength deficits were seen in knee flexion strength in the hamstring group than the revision group (-38.90±16.21% vs -28.13±23.22%, p=0.009) which had significantly greater knee flexion strength deficits than the patellar tendon group (-28.13±23.22% vs -1.17±12.41%, p=0.001). The hamstring primary group also showed greater triple hop deficit (-21.08±25.99%) than the other two groups (-21.08±25.99% vs -10.75±12.85 vs -6.84±23.81, p=0.024), which were similar. CONCLUSIONS: After revision ACLR with a second autograft from the same knee, adolescents show similar knee extension strength deficits compared to primary ACL patients with patellar tendon grafts, but improved knee flexion strength deficits compared to primary ACL patients with hamstring grafts. TABLES/FIGURES:
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spelling pubmed-82845242021-07-30 FUNCTIONAL RECOVERY AFTER REVISION ACL RECONSTRUCTION WITH A SECOND AUTOGRAFT: A MATCHED COHORT ANALYSIS IN ADOLESCENT PATIENTS Wilson, Benjamin R. Heyworth, Benton E. Coene, Ryan P. Sugimoto, Dai Micheli, Lyle J. Kocher, Mininder S. Christino, Melissa A. Orthop J Sports Med Article BACKGROUND: Young patients are the highest risk demographic for ACL graft failure and revision surgery. Previous studies have shown higher rates of graft failure with the use of allograft tissue for ACL reconstruction (ACLR) in both primary and revision surgeries. However, questions remain regarding the functional consequence of taking a second autograft from the same knee for revision ACLR. PURPOSE: The purpose of this study was to evaluate 6-month functional testing in patients who underwent revision ACLR with a second autograft from the same knee compared to matched cohorts of primary ACL patients. METHODS: We retrospectively reviewed prospectively collected data from patients aged 19 or younger who had revision ACLR with a second autograft at our institution. We excluded patients with iliotibial band autografts, two autografts from a synergistic muscle groups, or grafts from the contralateral knee. Patients with previous significant injury or surgery to the contralateral leg, and those with multiligamentous knee injuries were excluded. Patients underwent functional testing 5-8 months after revision surgery including anthropometric measures, isometric strength, Y-Balance, and hop testing. Side-to-side deficits were then compared to age, sex, and BMI matched cohorts of primary ACLR patients, with hamstring or patellar tendon autografts. Multivariate analysis of variance (MANOVA) was used, and if significance was detected, pairwise comparison was performed by Bonferroni post-hoc correction. Statistical significance of p<0.05 was applied. RESULTS: Thirty-seven adolescents underwent functional testing at 6.25±0.56 months after revision ACLR with a second autograft. These patients were matched to 62 patients who underwent primary ACLR with hamstring autograft, and 47 who underwent ACLR with patellar tendon autograft (Table 1). Revision ACLR patients showed comparable knee extension strength deficits to the patellar tendon group (-9.45±12.09% vs -8.81±13.83%, p=0.999) which were significantly greater than hamstring group (-9.45±12.09% vs -0.99±12.00%, p<0.05). Greater strength deficits were seen in knee flexion strength in the hamstring group than the revision group (-38.90±16.21% vs -28.13±23.22%, p=0.009) which had significantly greater knee flexion strength deficits than the patellar tendon group (-28.13±23.22% vs -1.17±12.41%, p=0.001). The hamstring primary group also showed greater triple hop deficit (-21.08±25.99%) than the other two groups (-21.08±25.99% vs -10.75±12.85 vs -6.84±23.81, p=0.024), which were similar. CONCLUSIONS: After revision ACLR with a second autograft from the same knee, adolescents show similar knee extension strength deficits compared to primary ACL patients with patellar tendon grafts, but improved knee flexion strength deficits compared to primary ACL patients with hamstring grafts. TABLES/FIGURES: SAGE Publications 2021-07-14 /pmc/articles/PMC8284524/ http://dx.doi.org/10.1177/2325967121S00107 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc-nd/4.0/This open-access article is published and distributed under the Creative Commons Attribution - NonCommercial - No Derivatives License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits the noncommercial use, distribution, and reproduction of the article in any medium, provided the original author and source are credited. You may not alter, transform, or build upon this article without the permission of the Author(s). For article reuse guidelines, please visit SAGE’s website at http://www.sagepub.com/journals-permissions.
spellingShingle Article
Wilson, Benjamin R.
Heyworth, Benton E.
Coene, Ryan P.
Sugimoto, Dai
Micheli, Lyle J.
Kocher, Mininder S.
Christino, Melissa A.
FUNCTIONAL RECOVERY AFTER REVISION ACL RECONSTRUCTION WITH A SECOND AUTOGRAFT: A MATCHED COHORT ANALYSIS IN ADOLESCENT PATIENTS
title FUNCTIONAL RECOVERY AFTER REVISION ACL RECONSTRUCTION WITH A SECOND AUTOGRAFT: A MATCHED COHORT ANALYSIS IN ADOLESCENT PATIENTS
title_full FUNCTIONAL RECOVERY AFTER REVISION ACL RECONSTRUCTION WITH A SECOND AUTOGRAFT: A MATCHED COHORT ANALYSIS IN ADOLESCENT PATIENTS
title_fullStr FUNCTIONAL RECOVERY AFTER REVISION ACL RECONSTRUCTION WITH A SECOND AUTOGRAFT: A MATCHED COHORT ANALYSIS IN ADOLESCENT PATIENTS
title_full_unstemmed FUNCTIONAL RECOVERY AFTER REVISION ACL RECONSTRUCTION WITH A SECOND AUTOGRAFT: A MATCHED COHORT ANALYSIS IN ADOLESCENT PATIENTS
title_short FUNCTIONAL RECOVERY AFTER REVISION ACL RECONSTRUCTION WITH A SECOND AUTOGRAFT: A MATCHED COHORT ANALYSIS IN ADOLESCENT PATIENTS
title_sort functional recovery after revision acl reconstruction with a second autograft: a matched cohort analysis in adolescent patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284524/
http://dx.doi.org/10.1177/2325967121S00107
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