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Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons
The formation and maintenance of microtubules requires their polymerisation, but little is known about how this polymerisation is regulated in cells. Focussing on the essential microtubule bundles in axons of Drosophila and Xenopus neurons, we show that the plus-end scaffold Eb1, the polymerase XMAP...
Autores principales: | Hahn, Ines, Voelzmann, Andre, Parkin, Jill, Fülle, Judith B., Slater, Paula G., Lowery, Laura Anne, Sanchez-Soriano, Natalia, Prokop, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284659/ https://www.ncbi.nlm.nih.gov/pubmed/34228717 http://dx.doi.org/10.1371/journal.pgen.1009647 |
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