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Cardiovascular disease and prevention among people living with HIV in South Florida
Antiretroviral therapy (ART) has improved survival of patients living with HIV (PLWH); however, this has been accompanied by an increase in cardiovascular disease (CVD). Although preventative measures for CVD among the general population are well described, information is limited about CVD preventio...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284739/ https://www.ncbi.nlm.nih.gov/pubmed/34260554 http://dx.doi.org/10.1097/MD.0000000000026631 |
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author | Pyarali, Fahim Iordanov, Roumen Ebner, Bertrand Grant, Jelani Vincent, Louis Toirac, Alexander Haque, Tahir Zablah, Gerardo Kapoor, Kunal Powell, Alexis Boulanger, Catherine Hurwitz, Barry Alcaide, Maria Martinez, Claudia |
author_facet | Pyarali, Fahim Iordanov, Roumen Ebner, Bertrand Grant, Jelani Vincent, Louis Toirac, Alexander Haque, Tahir Zablah, Gerardo Kapoor, Kunal Powell, Alexis Boulanger, Catherine Hurwitz, Barry Alcaide, Maria Martinez, Claudia |
author_sort | Pyarali, Fahim |
collection | PubMed |
description | Antiretroviral therapy (ART) has improved survival of patients living with HIV (PLWH); however, this has been accompanied by an increase in cardiovascular disease (CVD). Although preventative measures for CVD among the general population are well described, information is limited about CVD prevention among PLWH. The goal of this study was to characterize the prevalence of CVD in our population and to assess the use of primary and secondary prevention. We performed a retrospective review of PLWH receiving primary care at a large academic center in Miami, Florida. We characterized the prevalence of CVD, CVD risk, and the use of aspirin and statins for primary and secondary CVD prevention. A total of 985 charts were reviewed (45% women, 55% men). Average age was 52.2 years. Average CD4 count was 568 cells/microL. 92.9% were receiving ART, and 71% were virologically suppressed. The median 10-year ASCVD risk was 7.3%. The prevalence of CVD was 10.4% (N = 102). The odds of having CVD was lower in patients on ART (OR 0.47, 95% CI: 0.25–0.90, P = .02). The use of medications for primary and secondary prevention of CVD based on current guidelines was low: 15% and 37% for aspirin respectively, and 25% and 44% for statins. CVD risk and rates of CVD are high among PLWH and receiving ART could protect against CVD. However, the use of medications for primary and secondary prevention is low. Increased awareness of CVD risk-reduction strategies is needed among providers of PLWH to decrease the burden of CVD. |
format | Online Article Text |
id | pubmed-8284739 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-82847392021-07-19 Cardiovascular disease and prevention among people living with HIV in South Florida Pyarali, Fahim Iordanov, Roumen Ebner, Bertrand Grant, Jelani Vincent, Louis Toirac, Alexander Haque, Tahir Zablah, Gerardo Kapoor, Kunal Powell, Alexis Boulanger, Catherine Hurwitz, Barry Alcaide, Maria Martinez, Claudia Medicine (Baltimore) 4850 Antiretroviral therapy (ART) has improved survival of patients living with HIV (PLWH); however, this has been accompanied by an increase in cardiovascular disease (CVD). Although preventative measures for CVD among the general population are well described, information is limited about CVD prevention among PLWH. The goal of this study was to characterize the prevalence of CVD in our population and to assess the use of primary and secondary prevention. We performed a retrospective review of PLWH receiving primary care at a large academic center in Miami, Florida. We characterized the prevalence of CVD, CVD risk, and the use of aspirin and statins for primary and secondary CVD prevention. A total of 985 charts were reviewed (45% women, 55% men). Average age was 52.2 years. Average CD4 count was 568 cells/microL. 92.9% were receiving ART, and 71% were virologically suppressed. The median 10-year ASCVD risk was 7.3%. The prevalence of CVD was 10.4% (N = 102). The odds of having CVD was lower in patients on ART (OR 0.47, 95% CI: 0.25–0.90, P = .02). The use of medications for primary and secondary prevention of CVD based on current guidelines was low: 15% and 37% for aspirin respectively, and 25% and 44% for statins. CVD risk and rates of CVD are high among PLWH and receiving ART could protect against CVD. However, the use of medications for primary and secondary prevention is low. Increased awareness of CVD risk-reduction strategies is needed among providers of PLWH to decrease the burden of CVD. Lippincott Williams & Wilkins 2021-07-16 /pmc/articles/PMC8284739/ /pubmed/34260554 http://dx.doi.org/10.1097/MD.0000000000026631 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | 4850 Pyarali, Fahim Iordanov, Roumen Ebner, Bertrand Grant, Jelani Vincent, Louis Toirac, Alexander Haque, Tahir Zablah, Gerardo Kapoor, Kunal Powell, Alexis Boulanger, Catherine Hurwitz, Barry Alcaide, Maria Martinez, Claudia Cardiovascular disease and prevention among people living with HIV in South Florida |
title | Cardiovascular disease and prevention among people living with HIV in South Florida |
title_full | Cardiovascular disease and prevention among people living with HIV in South Florida |
title_fullStr | Cardiovascular disease and prevention among people living with HIV in South Florida |
title_full_unstemmed | Cardiovascular disease and prevention among people living with HIV in South Florida |
title_short | Cardiovascular disease and prevention among people living with HIV in South Florida |
title_sort | cardiovascular disease and prevention among people living with hiv in south florida |
topic | 4850 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284739/ https://www.ncbi.nlm.nih.gov/pubmed/34260554 http://dx.doi.org/10.1097/MD.0000000000026631 |
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