In vivo survival and differentiation of Friedreich ataxia iPSC‐derived sensory neurons transplanted in the adult dorsal root ganglia

Friedreich ataxia (FRDA) is an autosomal recessive disease characterized by degeneration of dorsal root ganglia (DRG) sensory neurons, which is due to low levels of the mitochondrial protein Frataxin. To explore cell replacement therapies as a possible approach to treat FRDA, we examined transplanta...

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Detalles Bibliográficos
Autores principales: Viventi, Serena, Frausin, Stefano, Howden, Sara E., Lim, Shiang Y., Finol‐Urdaneta, Rocio K., McArthur, Jeffrey R., Abu‐Bonsrah, Kwaku Dad, Ng, Wayne, Ivanusic, Jason, Thompson, Lachlan, Dottori, Mirella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Enabling Technologies for Cell‐Based Clinical Translation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284774/
https://www.ncbi.nlm.nih.gov/pubmed/33734599
http://dx.doi.org/10.1002/sctm.20-0334

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