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Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinases 1 (TIMP-1) are localized in the nucleus of retinal Müller glial cells and modulated by cytokines and oxidative stress

Matrix metalloproteinases (MMPs) are involved in the pathology of numerous inflammatory retinal degenerations, including retinitis pigmentosa (RP). Our previous work revealed that intravitreal injections with tissue inhibitor of metalloproteinases 1 (TIMP-1) reduce the progression of rod cell death...

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Detalles Bibliográficos
Autores principales: Lee, Eun-Jin, Zheng, Mengmei, Craft, Cheryl Mae, Jeong, Shinwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284794/
https://www.ncbi.nlm.nih.gov/pubmed/34270579
http://dx.doi.org/10.1371/journal.pone.0253915