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PCNA activates the MutLγ endonuclease to promote meiotic crossing over

During meiosis, crossover recombination connects homologous chromosomes to direct their accurate segregation(1). Defective crossing over causes infertility, miscarriage and congenital disease. Accordingly, each pair of chromosomes attains at least one crossover through processes that designate and t...

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Detalles Bibliográficos
Autores principales:	Kulkarni, Dhananjaya S., Owens, Shannon N., Honda, Masayoshi, Ito, Masaru, Yang, Ye, Corrigan, Mary W., Chen, Lan, Quan, Aric L., Hunter, Neil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284803/ https://www.ncbi.nlm.nih.gov/pubmed/32814343 http://dx.doi.org/10.1038/s41586-020-2645-6

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