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Aging-related upregulation of the homeobox gene caudal represses intestinal stem cell differentiation in Drosophila
The differentiation efficiency of adult stem cells undergoes a significant decline in aged animals, which is closely related to the decline in organ function and age-associated diseases. However, the underlying mechanisms that ultimately lead to this observed decline of the differentiation efficienc...
Autores principales: | Wu, Kun, Tang, Yiming, Zhang, Qiaoqiao, Zhuo, Zhangpeng, Sheng, Xiao, Huang, Jingping, Ye, Jie’er, Li, Xiaorong, Liu, Zhiming, Chen, Haiyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284806/ https://www.ncbi.nlm.nih.gov/pubmed/34228720 http://dx.doi.org/10.1371/journal.pgen.1009649 |
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