FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure

The mechanisms maintaining adult lymphatic vascular specialization throughout life and their role in coordinating inter-organ communication to sustain homeostasis remain elusive. We report that inactivation of the mechanosensitive transcription factor Foxc2 in adult lymphatic endothelium leads to a...

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Detalles Bibliográficos
Autores principales: González-Loyola, Alejandra, Bovay, Esther, Kim, Jaeryung, Lozano, Tania Wyss, Sabine, Amélie, Renevey, Francois, Arroz-Madeira, Silvia, Rapin, Alexis, Wypych, Tomasz P., Rota, Giorgia, Durot, Stephan, Velin, Dominique, Marsland, Benjamin, Guarda, Greta, Delorenzi, Mauro, Zamboni, Nicola, Luther, Sanjiv A., Petrova, Tatiana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8284898/
https://www.ncbi.nlm.nih.gov/pubmed/34272244
http://dx.doi.org/10.1126/sciadv.abf4335

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