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Mitochondrial Protection and Against Glutamate Neurotoxicity via Shh/Ptch1 Signaling Pathway to Ameliorate Cognitive Dysfunction by Kaixin San in Multi-Infarct Dementia Rats

Multi-infarct dementia (MID), a prominent subtype of vascular dementia (VD), is responsible for at least 15 to 20 percent of dementia in the elderly. Mitochondrial dysfunctions and glutamate neurotoxicity due to chronic hypoperfusion and oxidative stress were regarded as the major risk factors in th...

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Detalles Bibliográficos
Autores principales:	Li, Xiaoqiong, Wen, Wen, Li, Ping, Fu, Ying, Chen, Hao, Wang, Fushun, Dai, Yuan, Xu, Shijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285175/ https://www.ncbi.nlm.nih.gov/pubmed/34306310 http://dx.doi.org/10.1155/2021/5590745

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