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The Emerging Role of Interleukin 1β (IL-1β) in Cancer Cachexia
Treatment of cancer cachexia remains an unmet need. The host-tumour interface and the resulting sequestration of the pro-inflammatory cytokine Il-1β is critical in cachexia development. Neuroinflammation mediated via IL-1β through the hypothalamic pituitary axis results in increased muscle proteolys...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285330/ https://www.ncbi.nlm.nih.gov/pubmed/33907915 http://dx.doi.org/10.1007/s10753-021-01429-8 |