Cargando…

The Emerging Role of Interleukin 1β (IL-1β) in Cancer Cachexia

Treatment of cancer cachexia remains an unmet need. The host-tumour interface and the resulting sequestration of the pro-inflammatory cytokine Il-1β is critical in cachexia development. Neuroinflammation mediated via IL-1β through the hypothalamic pituitary axis results in increased muscle proteolys...

Descripción completa

Detalles Bibliográficos
Autores principales:	Laird, Barry J., McMillan, Donald, Skipworth, Richard J. E., Fallon, Marie T., Paval, D. Robert, McNeish, Iain, Gallagher, Iain J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285330/ https://www.ncbi.nlm.nih.gov/pubmed/33907915 http://dx.doi.org/10.1007/s10753-021-01429-8

Ejemplares similares

A systematic review examining the relationship between cytokines and cachexia in incurable cancer
por: Paval, D. Robert, et al.
Publicado: (2022)

Cancer cachexia: a nutritional or a systemic inflammatory syndrome?
por: McGovern, Josh, et al.
Publicado: (2022)

The Emerging Role of Intelectin-1 in Cancer
por: Paval, D. Robert, et al.
Publicado: (2022)

Physical function endpoints in cancer cachexia clinical trials: Systematic Review 1 of the cachexia endpoints series
por: McDonald, James, et al.
Publicado: (2023)

Adipose depot gene expression and intelectin‐1 in the metabolic response to cancer and cachexia
por: Miller, Janice, et al.
Publicado: (2020)

The prognostic impact of pre-treatment cachexia in resectional surgery for oesophagogastric cancer: a meta-analysis and meta-regression
por: Brown, Leo R, et al.
Publicado: (2023)

Lactate dehydrogenase: relationship with the diagnostic GLIM criterion for cachexia in patients with advanced cancer
por: McGovern, Josh, et al.
Publicado: (2022)

Understanding Cancer Cachexia and Its Implications in Upper Gastrointestinal Cancers
por: Brown, Leo R., et al.
Publicado: (2022)

Strategies to Optimise Oncolytic Viral Therapies: The Role of Natural Killer Cells
por: Leung, Elaine Y. L., et al.
Publicado: (2021)

Evaluating potential biomarkers of cachexia and survival in skeletal muscle of upper gastrointestinal cancer patients
por: Stephens, Nathan A, et al.
Publicado: (2015)

REVOLUTION (Routine EValuatiOn of people LivIng with caNcer)—Protocol for a prospective characterisation study of patients with incurable cancer
por: Patton, Rebekah, et al.
Publicado: (2021)

The potential and challenges of targeting MTAP-negative cancers beyond synthetic lethality
por: Bray, Chandler, et al.
Publicado: (2023)

Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia
por: Stephens, Nathan A, et al.
Publicado: (2010)

Influence of Polymorphism in the Genes for the Interleukin (IL)-1 Receptor Antagonist and IL-1β on Tuberculosis
por: Wilkinson, Robert J., et al.
Publicado: (1999)

Practical guidance for the management of side effects during rucaparib therapy in a multidisciplinary UK setting
por: Tookman, Laura, et al.
Publicado: (2020)

The role of cytokines in seizures: interleukin (IL)-1β, IL-1Ra, IL-8, and IL-10
por: Youn, Youngah, et al.
Publicado: (2013)

CD40 ligand induced cytotoxicity in carcinoma cells is enhanced by inhibition of metalloproteinase cleavage and delivery via a conditionally-replicating adenovirus
por: Elmetwali, Taha, et al.
Publicado: (2010)

Insulin Resistance Is Associated with Interleukin 1β (IL-1β) in Non-Diabetic Hemodialysis Patients
por: Bi, Xiao, et al.
Publicado: (2018)

Omentin-1 alleviate interleukin-1β(IL-1β)-induced nucleus pulposus cells senescence
por: Huang, Xin, et al.
Publicado: (2022)

Production of Mice Deficient in Genes for Interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 Receptor Antagonist Shows that IL-1β Is Crucial in Turpentine-induced Fever Development and Glucocorticoid Secretion
por: Horai, Reiko, et al.
Publicado: (1998)

Analysis of serum interleukin(IL)‐1α, IL‐1β and IL‐18 in patients with systemic sclerosis
por: Lin, Emily, et al.
Publicado: (2019)

Analysis of Serum Interleukin (IL)-1β and IL-18 in Systemic Lupus Erythematosus
por: Mende, Rachel, et al.
Publicado: (2018)

Development and validation of a house finch interleukin-1β (HfIL-1β) ELISA system
por: Kim, Sungwon, et al.
Publicado: (2017)

Interleukin-1β (IL-1β) & IL-4 gene polymorphisms in patients with systemic lupus erythematosus (SLE) & their association with susceptibility to SLE
por: Mohammadoo-khorasani, Milad, et al.
Publicado: (2016)

Cholera Toxin Suppresses Interleukin (IL)-12 Production and IL-12 Receptor β1 and β2 Chain Expression
por: Braun, Michael C., et al.
Publicado: (1999)

The Role of Interleukin-1 cytokine family (IL-1β, IL-37) and interleukin-12 cytokine family (IL-12, IL-35) in eumycetoma infection pathogenesis
por: Abushouk, Amir, et al.
Publicado: (2019)

Interleukin (IL) -1 β, IL-6 and tumor necrosis factor in patients with seasonal flu
por: Ramos, José M., et al.
Publicado: (2018)

Varicella-Zoster Virus Infection Triggers Formation of an Interleukin-1β (IL-1β)-processing Inflammasome Complex
por: Nour, Adel M., et al.
Publicado: (2011)

Interleukin-1beta (IL-1β)-induced Notch ligand Jagged1 suppresses mitogenic action of IL-1β on human dystrophic myogenic cells
por: Nagata, Yuki, et al.
Publicado: (2017)

Negative and reversible feedback inhibition of the endothelial nitric oxide (NO) synthesis by interleukin-1β (IL-1β)-induced generation of nitric oxide
por: Kessler, P, et al.
Publicado: (1997)

Polo Like Kinase 2 Tumour Suppressor and cancer biomarker: new perspectives on drug sensitivity/resistance in cancer
por: Coley, Helen M., et al.
Publicado: (2012)

Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 Cleavage
por: Edye, Michelle E., et al.
Publicado: (2015)

Editorial: Rising stars in vascular physiology: 2022
por: Tulis, David A., et al.
Publicado: (2023)

Intramyocellular lipid droplets increase with progression of cachexia in cancer patients
por: Stephens, Nathan A., et al.
Publicado: (2011)

Interleukin-1β and Cancer
por: Rébé, Cédric, et al.
Publicado: (2020)

Functional identification of the zebrafish Interleukin-1 receptor in an embryonic model of Il-1β-induced systemic inflammation
por: Sebo, Dylan J., et al.
Publicado: (2022)

Vaccinia Virus Induces Programmed Necrosis in Ovarian Cancer Cells
por: Whilding, Lynsey M, et al.
Publicado: (2013)

Oncologist-led BRCA ‘mainstreaming’ in the ovarian cancer clinic: A study of 255 patients and its impact on their management
por: Rumford, Megan, et al.
Publicado: (2020)

Residual Type 1 Immunity in Patients Genetically Deficient for Interleukin 12 Receptor β1 (IL-12Rβ1): Evidence for an IL-12Rβ1–Independent Pathway of IL-12 Responsiveness in Human T Cells
por: Verhagen, Claudia E., et al.
Publicado: (2000)

Activation of brain interleukin-1β in schizophrenia
por: Söderlund, J, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_vdbbr1704dntignt75pkpoij6v