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The role of β-hairpin conformation in ester hydrolysis peptide catalysts based on a TrpZip scaffold
To explore the role of peptide conformation on catalytic activity in the context of ester hydrolysis catalysts, pairs of sequences were designed that contained or lacked β-hairpin character. For the hydrolysis of para-nitrophenylacetate in aqueous media, we found small but consistent trends wherein...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285361/ https://www.ncbi.nlm.nih.gov/pubmed/34354822 http://dx.doi.org/10.1039/d1ra04288b |