Cargando…

Targeting TLR4 Signaling to Blunt Viral-Mediated Acute Lung Injury

Respiratory viral infections have been a long-standing global burden ranging from seasonal recurrences to the unexpected pandemics. The yearly hospitalizations from seasonal viruses such as influenza can fluctuate greatly depending on the circulating strain(s) and the congruency with the predicted s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shirey, Kari Ann, Blanco, Jorge C. G., Vogel, Stefanie N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285366/ https://www.ncbi.nlm.nih.gov/pubmed/34282358 http://dx.doi.org/10.3389/fimmu.2021.705080

Ejemplares similares

Protection against influenza-induced Acute Lung Injury (ALI) by enhanced induction of M2a macrophages: possible role of PPARγ/RXR ligands in IL-4-induced M2a macrophage differentiation
por: Gopalakrishnan, Archana, et al.
Publicado: (2022)

The θ‐defensin retrocyclin 101 inhibits TLR4‐ and TLR2‐dependent signaling and protects mice against influenza infection
por: Prantner, Daniel, et al.
Publicado: (2017)

Novel Role of Gastric Releasing Peptide (GRP)-Mediated Signaling in the Host Response to Influenza Infection
por: Shirey, Kari Ann, et al.
Publicado: (2018)

Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections
por: Patel, Mira C., et al.
Publicado: (2018)

Respiratory Syncytial Virus Fusion Protein-Induced Toll-Like Receptor 4 (TLR4) Signaling Is Inhibited by the TLR4 Antagonists Rhodobacter sphaeroides Lipopolysaccharide and Eritoran (E5564) and Requires Direct Interaction with MD-2
por: Rallabhandi, Prasad, et al.
Publicado: (2012)

Role of the Lipoxygenase Pathway in RSV-induced Alternatively Activated Macrophages Leading to Resolution of Lung Pathology
por: Shirey, Kari Ann, et al.
Publicado: (2013)

TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection
por: Perrin-Cocon, Laure, et al.
Publicado: (2017)

TLR7/TLR9- and B Cell Receptor-Signaling Crosstalk: Promotion of Potentially Dangerous B Cells
por: Suthers, Amy N., et al.
Publicado: (2017)

Alarmin S100A8 Activates Alveolar Epithelial Cells in the Context of Acute Lung Injury in a TLR4-Dependent Manner
por: Chakraborty, Deblina, et al.
Publicado: (2017)

M2a macrophages facilitate resolution of chemically-induced colitis in TLR4-SNP mice
por: Vlk, Alexandra M., et al.
Publicado: (2023)

Select targeting of intracellular Toll-interleukin-1 receptor resistance domains for protection against influenza-induced disease
por: Shirey, Kari Ann, et al.
Publicado: (2020)

Differential Response of Gestational Tissues to TLR3 Viral Priming Prior to Exposure to Bacterial TLR2 and TLR2/6 Agonists
por: Rasheed, Zahirrah B. M., et al.
Publicado: (2020)

Penehyclidine hydrochloride inhibits TLR4 signaling and inflammation, and attenuates blunt chest trauma and hemorrhagic shock-induced acute lung injury in rats
por: Wu, Xiao-Jing, et al.
Publicado: (2018)

Demethyleneberberine alleviated the inflammatory response by targeting MD-2 to inhibit the TLR4 signaling
por: Zhao, Yaxing, et al.
Publicado: (2023)

Rhodobacter azotoformans LPS (RAP99-LPS) Is a TLR4 Agonist That Inhibits Lung Metastasis and Enhances TLR3-Mediated Chemokine Expression
por: Murakami, Kaoru, et al.
Publicado: (2021)

Macrophage TLR4 and PAR2 Signaling: Role in Regulating Vascular Inflammatory Injury and Repair
por: Rayees, Sheikh, et al.
Publicado: (2020)

Qinhuo Shanggan oral solution resolves acute lung injury by down-regulating TLR4/NF-κB signaling cascade and inhibiting NLRP3 inflammasome activation
por: Tang, Shun, et al.
Publicado: (2023)

Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody
por: Gebremeskel, Simon, et al.
Publicado: (2021)

Critical role of TLR activation in viral replication, persistence, and pathogenicity of Theiler’s virus
por: Kim, Byung S.
Publicado: (2023)

Purinergic Signaling to Terminate TLR Responses in Macrophages
por: Hamidzadeh, Kajal, et al.
Publicado: (2016)

Signaling via TLR2 and TLR4 Directly Down-Regulates T Cell Effector Functions: The Regulatory Face of Danger Signals
por: Zanin-Zhorov, Alexandra, et al.
Publicado: (2013)

A mouse model of human TLR4 D299G/T399I SNPs reveals mechanisms of altered LPS and pathogen responses
por: Richard, Katharina, et al.
Publicado: (2020)

TLR7 Signaling Shapes and Maintains Antibody Diversity Upon Virus-Like Particle Immunization
por: Chang, Xinyue, et al.
Publicado: (2022)

Regulation of Toll-Like Receptor (TLR) Signaling Pathway by Polyphenols in the Treatment of Age-Linked Neurodegenerative Diseases: Focus on TLR4 Signaling
por: Azam, Shofiul, et al.
Publicado: (2019)

Mannose Receptor Mediates the Activation of Chitooligosaccharides on Blunt Snout Bream (Megalobrama amblycephala) Macrophages
por: Ouyang, Aotian, et al.
Publicado: (2021)

TLR signaling in mast cells: common and unique features
por: Sandig, Hilary, et al.
Publicado: (2012)

Thoroughly Remold the Localization and Signaling Pathway of TLR22
por: Ji, Jianfei, et al.
Publicado: (2020)

TLR7 Signaling Drives the Development of Sjögren’s Syndrome
por: Wang, Yawen, et al.
Publicado: (2021)

Influenza “Trains” the Host for Enhanced Susceptibility to Secondary Bacterial Infection
por: Shirey, Kari Ann, et al.
Publicado: (2019)

Activation of Both TLR and NOD Signaling Confers Host Innate Immunity-Mediated Protection Against Microbial Infection
por: Zhou, Huiting, et al.
Publicado: (2019)

P2Y6 receptor-mediated signaling amplifies TLR-induced pro-inflammatory responses in microglia
por: Timmerman, Raissa, et al.
Publicado: (2022)

TLR4-Mediated Blunting of Inflammatory Responses to Eccentric Exercise in Young Women
por: Fernandez-Gonzalo, Rodrigo, et al.
Publicado: (2014)

Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia
por: Wang, Xue, et al.
Publicado: (2022)

ACT001 Inhibits TLR4 Signaling by Targeting Co-Receptor MD2 and Attenuates Neuropathic Pain
por: Zhang, Tianshu, et al.
Publicado: (2022)

TLR7 Controls VSV Replication in CD169(+) SCS Macrophages and Associated Viral Neuroinvasion
por: Solmaz, Gülhas, et al.
Publicado: (2019)

TLR7 Is Critical for Anti-Viral Humoral Immunity to EV71 Infection in the Spinal Cord
por: Lin, Ya-Lin, et al.
Publicado: (2021)

Transcriptomic Analysis and C-Terminal Epitope Tagging Reveal Differential Processing and Signaling of Endogenous TLR3 and TLR7
por: Chen, Chiung-Ya, et al.
Publicado: (2021)

The TLR4-MyD88 Signaling Axis Regulates Lung Monocyte Differentiation Pathways in Response to Streptococcus pneumoniae
por: Sánchez-Tarjuelo, Rodrigo, et al.
Publicado: (2020)

Macrophage MMP10 Regulates TLR7-Mediated Tolerance
por: Rohani, Maryam G., et al.
Publicado: (2018)

Cytokine-Mediated Tissue Injury in Non-human Primate Models of Viral Infections
por: Manickam, Cordelia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_7u4qia2kfc80c6gag922l480ge