The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo

Poised enhancers (PEs) represent a genetically distinct set of distal regulatory elements that control the expression of major developmental genes. Before becoming activated in differentiating cells, PEs are already bookmarked in pluripotent cells with unique chromatin and topological features that...

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Detalles Bibliográficos
Autores principales: Crispatzu, Giuliano, Rehimi, Rizwan, Pachano, Tomas, Bleckwehl, Tore, Cruz-Molina, Sara, Xiao, Cally, Mahabir, Esther, Bazzi, Hisham, Rada-Iglesias, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285398/
https://www.ncbi.nlm.nih.gov/pubmed/34272393
http://dx.doi.org/10.1038/s41467-021-24641-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285398/
https://www.ncbi.nlm.nih.gov/pubmed/34272393
http://dx.doi.org/10.1038/s41467-021-24641-4

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