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The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo
Poised enhancers (PEs) represent a genetically distinct set of distal regulatory elements that control the expression of major developmental genes. Before becoming activated in differentiating cells, PEs are already bookmarked in pluripotent cells with unique chromatin and topological features that...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285398/ https://www.ncbi.nlm.nih.gov/pubmed/34272393 http://dx.doi.org/10.1038/s41467-021-24641-4 |