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Si-C is a method for inferring super-resolution intact genome structure from single-cell Hi-C data

There is a strong demand for methods that can efficiently reconstruct valid super-resolution intact genome 3D structures from sparse and noise single-cell Hi-C data. Here, we develop Single-Cell Chromosome Conformation Calculator (Si-C) within the Bayesian theory framework and apply this approach to...

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Detalles Bibliográficos
Autores principales:	Meng, Luming, Wang, Chenxi, Shi, Yi, Luo, Qiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285481/ https://www.ncbi.nlm.nih.gov/pubmed/34272403 http://dx.doi.org/10.1038/s41467-021-24662-z

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