Cellular senescence promotes endothelial activation through epigenetic alteration, and consequently accelerates atherosclerosis

Senescent vascular cells are detected in atherosclerotic lesion, and its involvement in the development of atherosclerosis has been revealed; however, whether and the mechanism by which endothelial cell (EC) senescence is causally implicated in atherosclerosis remains unclear. We here investigate a...

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Detalles Bibliográficos
Autores principales: Honda, Sakiko, Ikeda, Koji, Urata, Ryota, Yamazaki, Ekura, Emoto, Noriaki, Matoba, Satoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285500/
https://www.ncbi.nlm.nih.gov/pubmed/34272458
http://dx.doi.org/10.1038/s41598-021-94097-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285500/
https://www.ncbi.nlm.nih.gov/pubmed/34272458
http://dx.doi.org/10.1038/s41598-021-94097-5

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