Cargando…
Cellular senescence promotes endothelial activation through epigenetic alteration, and consequently accelerates atherosclerosis
Senescent vascular cells are detected in atherosclerotic lesion, and its involvement in the development of atherosclerosis has been revealed; however, whether and the mechanism by which endothelial cell (EC) senescence is causally implicated in atherosclerosis remains unclear. We here investigate a...
Autores principales: | Honda, Sakiko, Ikeda, Koji, Urata, Ryota, Yamazaki, Ekura, Emoto, Noriaki, Matoba, Satoaki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285500/ https://www.ncbi.nlm.nih.gov/pubmed/34272458 http://dx.doi.org/10.1038/s41598-021-94097-5 |
Ejemplares similares
-
Spermidine improves angiogenic capacity of senescent endothelial cells, and enhances ischemia-induced neovascularization in aged mice
por: Ueno, Daisuke, et al.
Publicado: (2023) -
Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype
por: Barinda, Agian Jeffilano, et al.
Publicado: (2020) -
Senescent endothelial cells are predisposed to SARS-CoV-2 infection and subsequent endothelial dysfunction
por: Urata, Ryota, et al.
Publicado: (2022) -
Publisher Correction: Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype
por: Barinda, Agian Jeffilano, et al.
Publicado: (2020) -
Endothelial cell senescence exacerbates pulmonary hypertension by inducing juxtacrine Notch signaling in smooth muscle cells
por: Ramadhiani, Risa, et al.
Publicado: (2023)