Mutation in FBXO32 causes dilated cardiomyopathy through up-regulation of ER-stress mediated apoptosis

Endoplasmic reticulum (ER) stress induction of cell death is implicated in cardiovascular diseases. Sustained activation of ER-stress induces the unfolded protein response (UPR) pathways, which in turn activate three major effector proteins. We previously reported a missense homozygous mutation in F...

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Detalles Bibliográficos
Autores principales: Al-Yacoub, Nadya, Colak, Dilek, Mahmoud, Salma Awad, Hammonds, Maya, Muhammed, Kunhi, Al-Harazi, Olfat, Assiri, Abdullah M., Al-Buraiki, Jehad, Al-Habeeb, Waleed, Poizat, Coralie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285540/
https://www.ncbi.nlm.nih.gov/pubmed/34272480
http://dx.doi.org/10.1038/s42003-021-02391-9

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