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The Atg16l1 gene: characterization of wild type, knock-in, and knock-out phenotypes in rats
ATG16L1 is a ubiquitous autophagy gene responsible, in part, for formation of the double-membrane bound autophagosome that delivers unwanted cellular debris and intracellular pathogens to the lysosome for degradation. A single, nonsynonymous adenine to guanine polymorphism resulting in a threonine t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Physiological Society
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285577/ https://www.ncbi.nlm.nih.gov/pubmed/33818130 http://dx.doi.org/10.1152/physiolgenomics.00114.2020 |