Calcium channel blockers do not protect against saturated fatty acid-induced ER stress and apoptosis in human pancreatic β-cells

It was evidenced that saturated fatty acids (FAs) have a detrimental effect on pancreatic β-cells function and survival, leading to endoplasmic reticulum (ER) calcium release, ER stress, and apoptosis. In the present study, we have tested the effect of three calcium influx inhibitors, i.e., diazoxid...

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Detalles Bibliográficos
Autores principales: Šrámek, Jan, Němcová, Vlasta, Kovář, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285784/
https://www.ncbi.nlm.nih.gov/pubmed/34274001
http://dx.doi.org/10.1186/s12986-021-00597-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285784/
https://www.ncbi.nlm.nih.gov/pubmed/34274001
http://dx.doi.org/10.1186/s12986-021-00597-6

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