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COVID‐19 vaccine (ChAdOx1 nCoV‐19 Corona virus vaccine (Recombinant) – COVISHIELD related MS relapse

BACKGROUND: there are very few reports of COVID-19 vaccine related multiple sclerosis (MS) relapses. Here we report our first case of ChAdOx1 nCoV-19 Corona virus vaccine related MS relapse. CASE PRESENTATION: a 24- year- old lady doctor, who had taken ChAdOx1 nCoV-19 Corona virus vaccine got a rela...

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Detalles Bibliográficos
Autores principales: Mathew, Thomas, John, Saji K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285929/
http://dx.doi.org/10.1016/j.nerep.2021.100006
Descripción
Sumario:BACKGROUND: there are very few reports of COVID-19 vaccine related multiple sclerosis (MS) relapses. Here we report our first case of ChAdOx1 nCoV-19 Corona virus vaccine related MS relapse. CASE PRESENTATION: a 24- year- old lady doctor, who had taken ChAdOx1 nCoV-19 Corona virus vaccine got a relapse after seven days of the last dose (second) of the vaccine. Relapse was in the form of paresthesias involving her left upper and lower limbs and Lhermitte's phenomena. She responded fairly well to a short course of steroids. CONCLUSIONS: this case highlights the importance of counselling MS patients regarding the potential for relapse pre-vaccination and closely monitoring MS patients who are administered the ChAdOx1 nCoV-19 Corona Virus vaccine for any relapse.