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Re-examination of the impact of some non-pharmaceutical interventions and media coverage on the COVID-19 outbreak in Wuhan()
In this paper, based on the classic Kermack-McKendrick SIR model, we propose an ordinary differential equation model to re-examine the COVID-19 epidemics in Wuhan where this disease initially broke out. The focus is on the impact of all those major non-pharmaceutical interventions (NPIs) implemented...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285935/ https://www.ncbi.nlm.nih.gov/pubmed/34307999 http://dx.doi.org/10.1016/j.idm.2021.07.001 |
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author | Li, Ao Wang, Yang Cong, Pingping Zou, Xingfu |
author_facet | Li, Ao Wang, Yang Cong, Pingping Zou, Xingfu |
author_sort | Li, Ao |
collection | PubMed |
description | In this paper, based on the classic Kermack-McKendrick SIR model, we propose an ordinary differential equation model to re-examine the COVID-19 epidemics in Wuhan where this disease initially broke out. The focus is on the impact of all those major non-pharmaceutical interventions (NPIs) implemented by the local public healthy authorities and government during the epidemics. We use the data publicly available and the nonlinear least-squares solver lsqnonlin built in MATLAB to estimate the model parameters. Then we explore the impact of those NPIs, particularly the timings of these interventions, on the epidemics. The results can help people review the responses to the outbreak of the COVID-19 in Wuhan, while the proposed model also offers a framework for studying epidemics of COVID-19 and/or other similar diseases in other places, and accordingly helping people better prepare for possible future outbreaks of similar diseases. |
format | Online Article Text |
id | pubmed-8285935 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | KeAi Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-82859352021-07-20 Re-examination of the impact of some non-pharmaceutical interventions and media coverage on the COVID-19 outbreak in Wuhan() Li, Ao Wang, Yang Cong, Pingping Zou, Xingfu Infect Dis Model Original Research Article In this paper, based on the classic Kermack-McKendrick SIR model, we propose an ordinary differential equation model to re-examine the COVID-19 epidemics in Wuhan where this disease initially broke out. The focus is on the impact of all those major non-pharmaceutical interventions (NPIs) implemented by the local public healthy authorities and government during the epidemics. We use the data publicly available and the nonlinear least-squares solver lsqnonlin built in MATLAB to estimate the model parameters. Then we explore the impact of those NPIs, particularly the timings of these interventions, on the epidemics. The results can help people review the responses to the outbreak of the COVID-19 in Wuhan, while the proposed model also offers a framework for studying epidemics of COVID-19 and/or other similar diseases in other places, and accordingly helping people better prepare for possible future outbreaks of similar diseases. KeAi Publishing 2021-07-17 /pmc/articles/PMC8285935/ /pubmed/34307999 http://dx.doi.org/10.1016/j.idm.2021.07.001 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Original Research Article Li, Ao Wang, Yang Cong, Pingping Zou, Xingfu Re-examination of the impact of some non-pharmaceutical interventions and media coverage on the COVID-19 outbreak in Wuhan() |
title | Re-examination of the impact of some non-pharmaceutical interventions and media coverage on the COVID-19 outbreak in Wuhan() |
title_full | Re-examination of the impact of some non-pharmaceutical interventions and media coverage on the COVID-19 outbreak in Wuhan() |
title_fullStr | Re-examination of the impact of some non-pharmaceutical interventions and media coverage on the COVID-19 outbreak in Wuhan() |
title_full_unstemmed | Re-examination of the impact of some non-pharmaceutical interventions and media coverage on the COVID-19 outbreak in Wuhan() |
title_short | Re-examination of the impact of some non-pharmaceutical interventions and media coverage on the COVID-19 outbreak in Wuhan() |
title_sort | re-examination of the impact of some non-pharmaceutical interventions and media coverage on the covid-19 outbreak in wuhan() |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285935/ https://www.ncbi.nlm.nih.gov/pubmed/34307999 http://dx.doi.org/10.1016/j.idm.2021.07.001 |
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