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Relationship of Gensini score with retinal vessel diameter and arteriovenous ratio in senile CHD

BACKGROUND: This study aimed to find the correlation of Gensini score with retinal vessel diameter and arteriovenous ratio in elderly patients with coronary heart disease (CHD). METHODS: This study included 120 senile CHD patients as the CHD group and 100 healthy individuals as the normal group (NG)...

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Autores principales: Wang, Ning, Liang, Changsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285989/
https://www.ncbi.nlm.nih.gov/pubmed/34316514
http://dx.doi.org/10.1515/biol-2021-0068
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author Wang, Ning
Liang, Changsen
author_facet Wang, Ning
Liang, Changsen
author_sort Wang, Ning
collection PubMed
description BACKGROUND: This study aimed to find the correlation of Gensini score with retinal vessel diameter and arteriovenous ratio in elderly patients with coronary heart disease (CHD). METHODS: This study included 120 senile CHD patients as the CHD group and 100 healthy individuals as the normal group (NG). Gensini score was used to evaluate the severity of coronary artery lesions. Central retinal artery equivalents (CRAE), central retinal venular equivalents (CRVE), and arteriovenous ratio (AVR) were measured. RESULTS: CHD group has lower CRAE and AVR than NG, while higher CRVE was observed in NG. CRAE and AVR in UAP (unstable angina pectoris) and AMI (acute myocardial infarction) groups showed reduction (stable angina pectoris); however, enhanced CRVE and Gensini scores in UA and AMI groups were observed as compared to the SAP group. CRAE and AVR in moderate and severe groups were reduced to a greater extent compared to the mild groups, while enhanced CRVE and Gensini scores were observed more often in the severe group than the mild group. CRAE and AVR were negatively correlated with the Gensini score; however, CRVE was positively correlated with the Gensini score. CONCLUSION: AVR is expected to be a noninvasive index to diagnose and predict senile CHD, which has a certain evaluation value. Diabetes, smoking history, and TC are independent risk factors of senile CHD.
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spelling pubmed-82859892021-07-26 Relationship of Gensini score with retinal vessel diameter and arteriovenous ratio in senile CHD Wang, Ning Liang, Changsen Open Life Sci Research Article BACKGROUND: This study aimed to find the correlation of Gensini score with retinal vessel diameter and arteriovenous ratio in elderly patients with coronary heart disease (CHD). METHODS: This study included 120 senile CHD patients as the CHD group and 100 healthy individuals as the normal group (NG). Gensini score was used to evaluate the severity of coronary artery lesions. Central retinal artery equivalents (CRAE), central retinal venular equivalents (CRVE), and arteriovenous ratio (AVR) were measured. RESULTS: CHD group has lower CRAE and AVR than NG, while higher CRVE was observed in NG. CRAE and AVR in UAP (unstable angina pectoris) and AMI (acute myocardial infarction) groups showed reduction (stable angina pectoris); however, enhanced CRVE and Gensini scores in UA and AMI groups were observed as compared to the SAP group. CRAE and AVR in moderate and severe groups were reduced to a greater extent compared to the mild groups, while enhanced CRVE and Gensini scores were observed more often in the severe group than the mild group. CRAE and AVR were negatively correlated with the Gensini score; however, CRVE was positively correlated with the Gensini score. CONCLUSION: AVR is expected to be a noninvasive index to diagnose and predict senile CHD, which has a certain evaluation value. Diabetes, smoking history, and TC are independent risk factors of senile CHD. De Gruyter 2021-07-16 /pmc/articles/PMC8285989/ /pubmed/34316514 http://dx.doi.org/10.1515/biol-2021-0068 Text en © 2021 Ning Wang and Changsen Liang, published by De Gruyter https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License.
spellingShingle Research Article
Wang, Ning
Liang, Changsen
Relationship of Gensini score with retinal vessel diameter and arteriovenous ratio in senile CHD
title Relationship of Gensini score with retinal vessel diameter and arteriovenous ratio in senile CHD
title_full Relationship of Gensini score with retinal vessel diameter and arteriovenous ratio in senile CHD
title_fullStr Relationship of Gensini score with retinal vessel diameter and arteriovenous ratio in senile CHD
title_full_unstemmed Relationship of Gensini score with retinal vessel diameter and arteriovenous ratio in senile CHD
title_short Relationship of Gensini score with retinal vessel diameter and arteriovenous ratio in senile CHD
title_sort relationship of gensini score with retinal vessel diameter and arteriovenous ratio in senile chd
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8285989/
https://www.ncbi.nlm.nih.gov/pubmed/34316514
http://dx.doi.org/10.1515/biol-2021-0068
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