Mesenchymal Stem Cell-Derived Exosomes Induced by IL-1β Attenuate Urethral Stricture Through Let-7c/PAK1/NF-κB-Regulated Macrophage M2 Polarization

BACKGROUND: Urethral stricture is a clinical challenge for both patients and clinicians. Post-traumatic urethral stricture is associated with formation of scar tissue caused by excessive inflammation. The aim of this study is exploring potential therapeutic strategies for this condition. METHODS: In...

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Detalles Bibliográficos
Autores principales: Chen, Ye-Hui, Dong, Ru-Nan, Hou, Jian, Lin, Ting-Ting, Chen, Shao-Hao, Chen, Hang, Zhu, Jun-Ming, Chen, Jia-Yin, Ke, Zhi-Bin, Lin, Fei, Xue, Xue-Yi, Wei, Yong, Xu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286124/
https://www.ncbi.nlm.nih.gov/pubmed/34285545
http://dx.doi.org/10.2147/JIR.S308405

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