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Sensory Stimulation Threshold: A Viable Tool to Improve the Outcome of Lumbar Facet Radiofrequency Denervation?

BACKGROUND: Sensory stimulation threshold (SST) has been used as a surrogate marker to target a nerve branch for radiofrequency (RF) denervation; however, the validity of SST as a prognostic marker is still under debate. OBJECTIVE: To assess whether lower SST values correlate with better outcomes of...

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Autores principales: Shi, Weibin, Rudra, Renuka, Vu, To-Nhu, Gordin, Yuri, Smith, Ryan, Kunselman, Allen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286126/
https://www.ncbi.nlm.nih.gov/pubmed/34285571
http://dx.doi.org/10.2147/JPR.S319622
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author Shi, Weibin
Rudra, Renuka
Vu, To-Nhu
Gordin, Yuri
Smith, Ryan
Kunselman, Allen R
author_facet Shi, Weibin
Rudra, Renuka
Vu, To-Nhu
Gordin, Yuri
Smith, Ryan
Kunselman, Allen R
author_sort Shi, Weibin
collection PubMed
description BACKGROUND: Sensory stimulation threshold (SST) has been used as a surrogate marker to target a nerve branch for radiofrequency (RF) denervation; however, the validity of SST as a prognostic marker is still under debate. OBJECTIVE: To assess whether lower SST values correlate with better outcomes of radiofrequency denervation for facetogenic low back pain. DESIGN: Prospective cohort study. PATIENTS: Sixty-seven patients who underwent radiofrequency denervation for low back pain. METHODS: Correlations, between the average percentage of pain relief from diagnostic medial branch block (MBB) and RF denervation procedure outcome, and between SST and RF denervation procedure outcome, were analyzed using Spearman correlation coefficient (r(s)). Wilcoxon rank sum test was performed to assess whether magnitude and duration of pain relief following RF denervation differed by the levels of SST (<0.5 and ≥0.5) or pain relief (<80% and ≥80%) from diagnostic MBB. RESULTS: There was a positive correlation between pain relief after diagnostic MBB and pain relief 2 weeks after denervation (r(s) 0.31, 95% CI 0.08 to 0.51, p < 0.01), but not between pain relief after MBB and pain relief 6 months after denervation, nor pain relief duration after denervation. There was a negative correlation between SST and pain relief 6 months after denervation (r(s) −0.41, 95% CI −0.59 to −0.18, p < 0.001). There was also a negative correlation between SST and pain relief duration after denervation (r(s) −0.33, 95% CI −0.53 to −0.09, p < 0.01). CONCLUSION: SST is a viable measurement with which to guide needle placement during RF denervation for lumbar facet pain, and enhances pain relief outcomes.
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spelling pubmed-82861262021-07-19 Sensory Stimulation Threshold: A Viable Tool to Improve the Outcome of Lumbar Facet Radiofrequency Denervation? Shi, Weibin Rudra, Renuka Vu, To-Nhu Gordin, Yuri Smith, Ryan Kunselman, Allen R J Pain Res Original Research BACKGROUND: Sensory stimulation threshold (SST) has been used as a surrogate marker to target a nerve branch for radiofrequency (RF) denervation; however, the validity of SST as a prognostic marker is still under debate. OBJECTIVE: To assess whether lower SST values correlate with better outcomes of radiofrequency denervation for facetogenic low back pain. DESIGN: Prospective cohort study. PATIENTS: Sixty-seven patients who underwent radiofrequency denervation for low back pain. METHODS: Correlations, between the average percentage of pain relief from diagnostic medial branch block (MBB) and RF denervation procedure outcome, and between SST and RF denervation procedure outcome, were analyzed using Spearman correlation coefficient (r(s)). Wilcoxon rank sum test was performed to assess whether magnitude and duration of pain relief following RF denervation differed by the levels of SST (<0.5 and ≥0.5) or pain relief (<80% and ≥80%) from diagnostic MBB. RESULTS: There was a positive correlation between pain relief after diagnostic MBB and pain relief 2 weeks after denervation (r(s) 0.31, 95% CI 0.08 to 0.51, p < 0.01), but not between pain relief after MBB and pain relief 6 months after denervation, nor pain relief duration after denervation. There was a negative correlation between SST and pain relief 6 months after denervation (r(s) −0.41, 95% CI −0.59 to −0.18, p < 0.001). There was also a negative correlation between SST and pain relief duration after denervation (r(s) −0.33, 95% CI −0.53 to −0.09, p < 0.01). CONCLUSION: SST is a viable measurement with which to guide needle placement during RF denervation for lumbar facet pain, and enhances pain relief outcomes. Dove 2021-07-13 /pmc/articles/PMC8286126/ /pubmed/34285571 http://dx.doi.org/10.2147/JPR.S319622 Text en © 2021 Shi et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Shi, Weibin
Rudra, Renuka
Vu, To-Nhu
Gordin, Yuri
Smith, Ryan
Kunselman, Allen R
Sensory Stimulation Threshold: A Viable Tool to Improve the Outcome of Lumbar Facet Radiofrequency Denervation?
title Sensory Stimulation Threshold: A Viable Tool to Improve the Outcome of Lumbar Facet Radiofrequency Denervation?
title_full Sensory Stimulation Threshold: A Viable Tool to Improve the Outcome of Lumbar Facet Radiofrequency Denervation?
title_fullStr Sensory Stimulation Threshold: A Viable Tool to Improve the Outcome of Lumbar Facet Radiofrequency Denervation?
title_full_unstemmed Sensory Stimulation Threshold: A Viable Tool to Improve the Outcome of Lumbar Facet Radiofrequency Denervation?
title_short Sensory Stimulation Threshold: A Viable Tool to Improve the Outcome of Lumbar Facet Radiofrequency Denervation?
title_sort sensory stimulation threshold: a viable tool to improve the outcome of lumbar facet radiofrequency denervation?
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286126/
https://www.ncbi.nlm.nih.gov/pubmed/34285571
http://dx.doi.org/10.2147/JPR.S319622
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