LncRNA LINC00525 suppresses p21 expression via mRNA decay and triplex‐mediated changes in chromatin structure in lung adenocarcinoma

BACKGROUND: Emerging evidence suggests that long noncoding RNAs (lncRNAs) play crucial roles in various cancers. In the present study, we aim to investigate the function and molecular mechanism of an up‐regulated and survival‐associated lncRNA, LINC00525, in lung adenocarcinoma (LUAD). METHODS: The...

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Detalles Bibliográficos
Autores principales: Fang, Panqi, Chen, Hao, Ma, Zhifei, Han, Chencheng, Yin, Wenda, Wang, Siwei, Zhu, Hongyu, Xia, Wenjia, Wang, Jie, Xu, Lin, Liu, Tongyan, Yin, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286138/
https://www.ncbi.nlm.nih.gov/pubmed/34105888
http://dx.doi.org/10.1002/cac2.12181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286138/
https://www.ncbi.nlm.nih.gov/pubmed/34105888
http://dx.doi.org/10.1002/cac2.12181

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