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Allergens and their associated small molecule ligands—their dual role in sensitization
Many allergens feature hydrophobic cavities that allow the binding of primarily hydrophobic small‐molecule ligands. Ligand‐binding specificities can be strict or promiscuous. Serum albumins from mammals and birds can assume multiple conformations that facilitate the binding of a broad spectrum of co...
Autores principales: | Chruszcz, Maksymilian, Chew, Fook Tim, Hoffmann‐Sommergruber, Karin, Hurlburt, Barry K., Mueller, Geoffrey A., Pomés, Anna, Rouvinen, Juha, Villalba, Mayte, Wöhrl, Birgitta M., Breiteneder, Heimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286345/ https://www.ncbi.nlm.nih.gov/pubmed/33866585 http://dx.doi.org/10.1111/all.14861 |
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