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A Study of the Outcome of Critically Ill Elderly Patients in a Tertiary Care Hospital Using SOFA Score

BACKGROUND: With a rapidly rising geriatric population, the magnitude of elderly patients requiring intensive care is a major cause of concern. Data on critically ill geriatric patients is scarce, especially in developing countries. AIM AND OBJECTIVE: The aim of the study is to identify the etiology...

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Autores principales: Chopra, Shivani, Pednekar, Sangeeta, Karnik, Niteen D, Londhe, Charulata, Pandey, Dharmendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286402/
https://www.ncbi.nlm.nih.gov/pubmed/34316145
http://dx.doi.org/10.5005/jp-journals-10071-23883
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author Chopra, Shivani
Pednekar, Sangeeta
Karnik, Niteen D
Londhe, Charulata
Pandey, Dharmendra
author_facet Chopra, Shivani
Pednekar, Sangeeta
Karnik, Niteen D
Londhe, Charulata
Pandey, Dharmendra
author_sort Chopra, Shivani
collection PubMed
description BACKGROUND: With a rapidly rising geriatric population, the magnitude of elderly patients requiring intensive care is a major cause of concern. Data on critically ill geriatric patients is scarce, especially in developing countries. AIM AND OBJECTIVE: The aim of the study is to identify the etiology, clinical profile, and outcome in elderly patients admitted to the intensive care unit (ICU) and to predict their survival using the sequential organ failure assessment (SOFA) score. MATERIALS AND METHODS: A prospective observational study was performed over a period of 18 months with analysis of 100 patients admitted to the ICU, above the age of 60 years, with multi-organ dysfunction. The outcome of discharge or death was studied using the SOFA score on admission, on day 2, and the delta SOFA score. RESULTS: In this study of 100 patients, 88% of patients were in the 60–70 years age-group. The number of male and female patients was equal. Seventy percent of patients had comorbidities, of which hypertension was most common. The two most common etiologies were acute febrile illness and pneumonia. The use of mechanical ventilation, inotropic support, and serum creatinine has a significant association with the outcome. The SOFA score at admission did not have a significant association, but the score at 48 hours and delta SOFA score co-related with the outcome of the patients. Sixty-four patients got discharged; thus, there was a survival rate of 64%. CONCLUSION: The SOFA score at 48 hours is the most sensitive predictor of outcome, followed closely by the delta SOFA score, as compared to the SOFA score on admission, for critically ill elderly patients. There is a significant association of use of mechanical ventilation, inotropic support, and serum creatinine with the outcome. HOW TO CITE THIS ARTICLE: Chopra S, Pednekar S, Karnik ND, Londhe C, Pandey D. A Study of the Outcome of Critically Ill Elderly Patients in a Tertiary Care Hospital Using SOFA Score. Indian J Crit Care Med 2021;25(6):655–659.
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spelling pubmed-82864022021-07-26 A Study of the Outcome of Critically Ill Elderly Patients in a Tertiary Care Hospital Using SOFA Score Chopra, Shivani Pednekar, Sangeeta Karnik, Niteen D Londhe, Charulata Pandey, Dharmendra Indian J Crit Care Med Original Article BACKGROUND: With a rapidly rising geriatric population, the magnitude of elderly patients requiring intensive care is a major cause of concern. Data on critically ill geriatric patients is scarce, especially in developing countries. AIM AND OBJECTIVE: The aim of the study is to identify the etiology, clinical profile, and outcome in elderly patients admitted to the intensive care unit (ICU) and to predict their survival using the sequential organ failure assessment (SOFA) score. MATERIALS AND METHODS: A prospective observational study was performed over a period of 18 months with analysis of 100 patients admitted to the ICU, above the age of 60 years, with multi-organ dysfunction. The outcome of discharge or death was studied using the SOFA score on admission, on day 2, and the delta SOFA score. RESULTS: In this study of 100 patients, 88% of patients were in the 60–70 years age-group. The number of male and female patients was equal. Seventy percent of patients had comorbidities, of which hypertension was most common. The two most common etiologies were acute febrile illness and pneumonia. The use of mechanical ventilation, inotropic support, and serum creatinine has a significant association with the outcome. The SOFA score at admission did not have a significant association, but the score at 48 hours and delta SOFA score co-related with the outcome of the patients. Sixty-four patients got discharged; thus, there was a survival rate of 64%. CONCLUSION: The SOFA score at 48 hours is the most sensitive predictor of outcome, followed closely by the delta SOFA score, as compared to the SOFA score on admission, for critically ill elderly patients. There is a significant association of use of mechanical ventilation, inotropic support, and serum creatinine with the outcome. HOW TO CITE THIS ARTICLE: Chopra S, Pednekar S, Karnik ND, Londhe C, Pandey D. A Study of the Outcome of Critically Ill Elderly Patients in a Tertiary Care Hospital Using SOFA Score. Indian J Crit Care Med 2021;25(6):655–659. Jaypee Brothers Medical Publishers 2021-06 /pmc/articles/PMC8286402/ /pubmed/34316145 http://dx.doi.org/10.5005/jp-journals-10071-23883 Text en Copyright © 2021; Jaypee Brothers Medical Publishers (P) Ltd. https://creativecommons.org/licenses/by-nc/4.0/© Jaypee Brothers Medical Publishers. 2021 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and non-commercial reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Original Article
Chopra, Shivani
Pednekar, Sangeeta
Karnik, Niteen D
Londhe, Charulata
Pandey, Dharmendra
A Study of the Outcome of Critically Ill Elderly Patients in a Tertiary Care Hospital Using SOFA Score
title A Study of the Outcome of Critically Ill Elderly Patients in a Tertiary Care Hospital Using SOFA Score
title_full A Study of the Outcome of Critically Ill Elderly Patients in a Tertiary Care Hospital Using SOFA Score
title_fullStr A Study of the Outcome of Critically Ill Elderly Patients in a Tertiary Care Hospital Using SOFA Score
title_full_unstemmed A Study of the Outcome of Critically Ill Elderly Patients in a Tertiary Care Hospital Using SOFA Score
title_short A Study of the Outcome of Critically Ill Elderly Patients in a Tertiary Care Hospital Using SOFA Score
title_sort study of the outcome of critically ill elderly patients in a tertiary care hospital using sofa score
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286402/
https://www.ncbi.nlm.nih.gov/pubmed/34316145
http://dx.doi.org/10.5005/jp-journals-10071-23883
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