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The Ominous Ouzo Party – A Case Series of Four Patients with Accidental Alkali Ingestion

BACKGROUND: Ingestion of alkaline fluids is a common problem, which can lead to perforations, strictures and malignancy. We present a rare case series of several patients who accidentally ingested the same alkaline substance in different doses. METHODS: We investigated four patients with accidental...

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Autores principales: Vetter, Marcel, Rath, Timo, Siebler, Jürgen, Waldner, Maximilian, Neurath, Markus F, Pfeifer, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286424/
https://www.ncbi.nlm.nih.gov/pubmed/34285537
http://dx.doi.org/10.2147/CEG.S320047
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author Vetter, Marcel
Rath, Timo
Siebler, Jürgen
Waldner, Maximilian
Neurath, Markus F
Pfeifer, Lukas
author_facet Vetter, Marcel
Rath, Timo
Siebler, Jürgen
Waldner, Maximilian
Neurath, Markus F
Pfeifer, Lukas
author_sort Vetter, Marcel
collection PubMed
description BACKGROUND: Ingestion of alkaline fluids is a common problem, which can lead to perforations, strictures and malignancy. We present a rare case series of several patients who accidentally ingested the same alkaline substance in different doses. METHODS: We investigated four patients with accidental ingestion of dishwashing liquid. All patients underwent gastroscopy within 24h after inpatient admission. Gastroesophageal lesions were classified according to the Zargar classification for corrosive ingestions. RESULTS: Esophagogastric lesions were predominantly found at the distal esophagus and the small curvature of the stomach. The severity of these lesions ranged from mild erosions (Zargar 2A) to marked necrosis (Zargar 3A). Our data suggest that the degree of these lesions correlated with the amount of ingested toxin and duration of the inpatient stay. However, a low symptom severity or inconspicuous otolaryngologic examination did not exclude severe gastroesophageal lesions. CONCLUSION: Our data suggest that the severity of gastroesophageal lesions correlates with the amount of ingested alkaline substance. Symptom burden and an otolaryngologic examination are not sufficiently predictive for the severity of gastroesophageal lesions. The composition and quantity of the swallowed liquid should be determined.
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spelling pubmed-82864242021-07-19 The Ominous Ouzo Party – A Case Series of Four Patients with Accidental Alkali Ingestion Vetter, Marcel Rath, Timo Siebler, Jürgen Waldner, Maximilian Neurath, Markus F Pfeifer, Lukas Clin Exp Gastroenterol Case Series BACKGROUND: Ingestion of alkaline fluids is a common problem, which can lead to perforations, strictures and malignancy. We present a rare case series of several patients who accidentally ingested the same alkaline substance in different doses. METHODS: We investigated four patients with accidental ingestion of dishwashing liquid. All patients underwent gastroscopy within 24h after inpatient admission. Gastroesophageal lesions were classified according to the Zargar classification for corrosive ingestions. RESULTS: Esophagogastric lesions were predominantly found at the distal esophagus and the small curvature of the stomach. The severity of these lesions ranged from mild erosions (Zargar 2A) to marked necrosis (Zargar 3A). Our data suggest that the degree of these lesions correlated with the amount of ingested toxin and duration of the inpatient stay. However, a low symptom severity or inconspicuous otolaryngologic examination did not exclude severe gastroesophageal lesions. CONCLUSION: Our data suggest that the severity of gastroesophageal lesions correlates with the amount of ingested alkaline substance. Symptom burden and an otolaryngologic examination are not sufficiently predictive for the severity of gastroesophageal lesions. The composition and quantity of the swallowed liquid should be determined. Dove 2021-07-13 /pmc/articles/PMC8286424/ /pubmed/34285537 http://dx.doi.org/10.2147/CEG.S320047 Text en © 2021 Vetter et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Series
Vetter, Marcel
Rath, Timo
Siebler, Jürgen
Waldner, Maximilian
Neurath, Markus F
Pfeifer, Lukas
The Ominous Ouzo Party – A Case Series of Four Patients with Accidental Alkali Ingestion
title The Ominous Ouzo Party – A Case Series of Four Patients with Accidental Alkali Ingestion
title_full The Ominous Ouzo Party – A Case Series of Four Patients with Accidental Alkali Ingestion
title_fullStr The Ominous Ouzo Party – A Case Series of Four Patients with Accidental Alkali Ingestion
title_full_unstemmed The Ominous Ouzo Party – A Case Series of Four Patients with Accidental Alkali Ingestion
title_short The Ominous Ouzo Party – A Case Series of Four Patients with Accidental Alkali Ingestion
title_sort ominous ouzo party – a case series of four patients with accidental alkali ingestion
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286424/
https://www.ncbi.nlm.nih.gov/pubmed/34285537
http://dx.doi.org/10.2147/CEG.S320047
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