Re-infection with a different SARS-CoV-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient

Immunocompromised patients who have a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection pose many clinical and public health challenges. We describe the case of a hematopoietic stem cell transplantation patient with lymphoma who had a protracted illness requiring three consecuti...

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Detalles Bibliográficos
Autores principales: Alshukairi, Abeer N., El-Kafrawy, Sherif A., Dada, Ashraf, Yasir, Muhammad, Yamani, Amani H., Saeedi, Mohammed F., Aljohaney, Ahmed, AlJohani, Naif I., Bahaudden, Husam A., Alam, Intikhab, Gojobori, Takashi, Radovanovic, Aleksandar, Alandijany, Thamir A., Othman, Norah A., Alsubhi, Tagreed L., Hassan, Ahmed M., Tolah, Ahmed M., Al-Tawfiq, Jaffar A., Zumla, Alimuddin, Azhar, Esam I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286546/
https://www.ncbi.nlm.nih.gov/pubmed/34289407
http://dx.doi.org/10.1016/j.ijid.2021.07.036
Descripción
Sumario:Immunocompromised patients who have a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection pose many clinical and public health challenges. We describe the case of a hematopoietic stem cell transplantation patient with lymphoma who had a protracted illness requiring three consecutive hospital admissions. Whole genome sequencing confirmed two different SARS-CoV-2 clades. Clinical management issues and the unanswered questions arising from this case are discussed.

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