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Re-infection with a different SARS-CoV-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient
Immunocompromised patients who have a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection pose many clinical and public health challenges. We describe the case of a hematopoietic stem cell transplantation patient with lymphoma who had a protracted illness requiring three consecuti...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286546/ https://www.ncbi.nlm.nih.gov/pubmed/34289407 http://dx.doi.org/10.1016/j.ijid.2021.07.036 |
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author | Alshukairi, Abeer N. El-Kafrawy, Sherif A. Dada, Ashraf Yasir, Muhammad Yamani, Amani H. Saeedi, Mohammed F. Aljohaney, Ahmed AlJohani, Naif I. Bahaudden, Husam A. Alam, Intikhab Gojobori, Takashi Radovanovic, Aleksandar Alandijany, Thamir A. Othman, Norah A. Alsubhi, Tagreed L. Hassan, Ahmed M. Tolah, Ahmed M. Al-Tawfiq, Jaffar A. Zumla, Alimuddin Azhar, Esam I |
author_facet | Alshukairi, Abeer N. El-Kafrawy, Sherif A. Dada, Ashraf Yasir, Muhammad Yamani, Amani H. Saeedi, Mohammed F. Aljohaney, Ahmed AlJohani, Naif I. Bahaudden, Husam A. Alam, Intikhab Gojobori, Takashi Radovanovic, Aleksandar Alandijany, Thamir A. Othman, Norah A. Alsubhi, Tagreed L. Hassan, Ahmed M. Tolah, Ahmed M. Al-Tawfiq, Jaffar A. Zumla, Alimuddin Azhar, Esam I |
author_sort | Alshukairi, Abeer N. |
collection | PubMed |
description | Immunocompromised patients who have a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection pose many clinical and public health challenges. We describe the case of a hematopoietic stem cell transplantation patient with lymphoma who had a protracted illness requiring three consecutive hospital admissions. Whole genome sequencing confirmed two different SARS-CoV-2 clades. Clinical management issues and the unanswered questions arising from this case are discussed. |
format | Online Article Text |
id | pubmed-8286546 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82865462021-07-20 Re-infection with a different SARS-CoV-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient Alshukairi, Abeer N. El-Kafrawy, Sherif A. Dada, Ashraf Yasir, Muhammad Yamani, Amani H. Saeedi, Mohammed F. Aljohaney, Ahmed AlJohani, Naif I. Bahaudden, Husam A. Alam, Intikhab Gojobori, Takashi Radovanovic, Aleksandar Alandijany, Thamir A. Othman, Norah A. Alsubhi, Tagreed L. Hassan, Ahmed M. Tolah, Ahmed M. Al-Tawfiq, Jaffar A. Zumla, Alimuddin Azhar, Esam I Int J Infect Dis Case Report Immunocompromised patients who have a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection pose many clinical and public health challenges. We describe the case of a hematopoietic stem cell transplantation patient with lymphoma who had a protracted illness requiring three consecutive hospital admissions. Whole genome sequencing confirmed two different SARS-CoV-2 clades. Clinical management issues and the unanswered questions arising from this case are discussed. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021-09 2021-07-18 /pmc/articles/PMC8286546/ /pubmed/34289407 http://dx.doi.org/10.1016/j.ijid.2021.07.036 Text en © 2021 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Case Report Alshukairi, Abeer N. El-Kafrawy, Sherif A. Dada, Ashraf Yasir, Muhammad Yamani, Amani H. Saeedi, Mohammed F. Aljohaney, Ahmed AlJohani, Naif I. Bahaudden, Husam A. Alam, Intikhab Gojobori, Takashi Radovanovic, Aleksandar Alandijany, Thamir A. Othman, Norah A. Alsubhi, Tagreed L. Hassan, Ahmed M. Tolah, Ahmed M. Al-Tawfiq, Jaffar A. Zumla, Alimuddin Azhar, Esam I Re-infection with a different SARS-CoV-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient |
title | Re-infection with a different SARS-CoV-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient |
title_full | Re-infection with a different SARS-CoV-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient |
title_fullStr | Re-infection with a different SARS-CoV-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient |
title_full_unstemmed | Re-infection with a different SARS-CoV-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient |
title_short | Re-infection with a different SARS-CoV-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient |
title_sort | re-infection with a different sars-cov-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286546/ https://www.ncbi.nlm.nih.gov/pubmed/34289407 http://dx.doi.org/10.1016/j.ijid.2021.07.036 |
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