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Intravenous administration of LPS activates the kynurenine pathway in healthy male human subjects: a prospective placebo-controlled cross-over trial

BACKGROUND: Administration of lipopolysaccharide (LPS) from Gram-negative bacteria, also known as the human endotoxemia model, is a standardized and safe model of human inflammation. Experimental studies have revealed that peripheral administration of LPS leads to induction of the kynurenine pathway...

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Detalles Bibliográficos
Autores principales: Millischer, Vincent, Heinzl, Matthias, Faka, Anthi, Resl, Michael, Trepci, Ada, Klammer, Carmen, Egger, Margot, Dieplinger, Benjamin, Clodi, Martin, Schwieler, Lilly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286561/
https://www.ncbi.nlm.nih.gov/pubmed/34273987
http://dx.doi.org/10.1186/s12974-021-02196-x