Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase

The COVID-19 pandemic has presented itself as one of the most critical public health challenges of the century, with SARS-CoV-2 being the third member of the Coronaviridae family to cause a fatal disease in humans. There is currently only one antiviral compound, remdesivir, that can be used for the...

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Detalles Bibliográficos
Autores principales: Basu, Souradeep, Mak, Tiffany, Ulferts, Rachel, Wu, Mary, Deegan, Tom, Fujisawa, Ryo, Tan, Kang Wei, Lim, Chew Theng, Basier, Clovis, Canal, Berta, Curran, Joseph F., Drury, Lucy S., McClure, Allison W., Roberts, Emma L., Weissmann, Florian, Zeisner, Theresa U., Beale, Rupert, Cowling, Victoria H., Howell, Michael, Labib, Karim, Diffley, John F.X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Biochemical Techniques & Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286817/
https://www.ncbi.nlm.nih.gov/pubmed/34198328
http://dx.doi.org/10.1042/BCJ20210219

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