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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease

SARS-CoV-2 is responsible for COVID-19, a human disease that has caused over 2 million deaths, stretched health systems to near-breaking point and endangered economies of countries and families around the world. Antiviral treatments to combat COVID-19 are currently lacking. Remdesivir, the only anti...

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Detalles Bibliográficos
Autores principales: Canal, Berta, Fujisawa, Ryo, McClure, Allison W., Deegan, Tom D., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Drury, Lucy S., Bertolin, Agustina P., Zeng, Jingkun, Beale, Rupert, Howell, Michael, Labib, Karim, Diffley, John F.X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286823/
https://www.ncbi.nlm.nih.gov/pubmed/34198324
http://dx.doi.org/10.1042/BCJ20210199