Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease

The COVID-19 pandemic has emerged as the biggest life-threatening disease of this century. Whilst vaccination should provide a long-term solution, this is pitted against the constant threat of mutations in the virus rendering the current vaccines less effective. Consequently, small molecule antivira...

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Detalles Bibliográficos
Autores principales: Lim, Chew Theng, Tan, Kang Wei, Wu, Mary, Ulferts, Rachel, Armstrong, Lee A., Ozono, Eiko, Drury, Lucy S., Milligan, Jennifer C., Zeisner, Theresa U., Zeng, Jingkun, Weissmann, Florian, Canal, Berta, Bineva-Todd, Ganka, Howell, Michael, O'Reilly, Nicola, Beale, Rupert, Kulathu, Yogesh, Labib, Karim, Diffley, John F.X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Biochemical Techniques & Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286840/
https://www.ncbi.nlm.nih.gov/pubmed/34198325
http://dx.doi.org/10.1042/BCJ20210244

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