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Profiling of hepatocellular carcinoma neoantigens reveals immune microenvironment and clonal evolution related patterns
OBJECTIVE: Neoantigens derived from tumor-specific genomic alterations have demonstrated great potential for immunotherapeutic interventions in cancers. However, the comprehensive profile of hepatocellular carcinoma (HCC) neoantigens and their complex interplay with immune microenvironment and tumor...
Autores principales: | Li, Zhenli, Chen, Geng, Cai, Zhixiong, Dong, Xiuqing, He, Lei, Qiu, Liman, Zeng, Yongyi, Liu, Xiaolong, Liu, Jingfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286898/ https://www.ncbi.nlm.nih.gov/pubmed/34321833 http://dx.doi.org/10.21147/j.issn.1000-9604.2021.03.08 |
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