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Potential Privilege of Maltodextrin-α-Tocopherol Nano-Micelles in Seizing Tacrolimus Renal Toxicity, Managing Rheumatoid Arthritis and Accelerating Bone Regeneration

BACKGROUND: Tacrolimus (TAC) is a powerful immunosuppressive agent whose therapeutic applicability is confined owing to its systemic side effects. OBJECTIVE: Herein, we harnessed a natural polymer based bioconjugate composed of maltodextrin and α-tocopherol (MD-α-TOC) to encapsulate TAC as an attemp...

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Detalles Bibliográficos
Autores principales: Helal, Hala M, Samy, Wael M, Kamoun, Elbadawy A, El-Fakharany, Esmail M, Abdelmonsif, Doaa A, Aly, Rania G, Mortada, Sana M, Sallam, Marwa A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8286967/
https://www.ncbi.nlm.nih.gov/pubmed/34290503
http://dx.doi.org/10.2147/IJN.S317409

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