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Expression of Rab Prenylation Pathway Genes and Relation to Disease Progression in Choroideremia

PURPOSE: Choroideremia results from the deficiency of Rab Escort Protein 1 (REP1), encoded by CHM, involved in the prenylation of Rab GTPases. Here, we investigate whether the transcription and expression of other genes involved in the prenylation of Rab proteins correlates with disease progression...

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Detalles Bibliográficos
Autores principales:	Fry, Lewis E., Patrício, Maria I., Jolly, Jasleen K., Xue, Kanmin, MacLaren, Robert E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287038/ https://www.ncbi.nlm.nih.gov/pubmed/34254989 http://dx.doi.org/10.1167/tvst.10.8.12

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