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Therapeutic Potential of Targeting Stromal Crosstalk-Mediated Immune Suppression in Pancreatic Cancer

The stroma-rich, immunosuppressive microenvironment is a hallmark of pancreatic ductal adenocarcinoma (PDA). Tumor cells and other cellular components of the tumor microenvironment, such as cancer associated fibroblasts, CD4(+) T cells and myeloid cells, are linked by a web of interactions. Their cr...

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Detalles Bibliográficos
Autores principales: Du, Wenting, Pasca di Magliano, Marina, Zhang, Yaqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287251/
https://www.ncbi.nlm.nih.gov/pubmed/34290984
http://dx.doi.org/10.3389/fonc.2021.682217