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Cardiovascular Issues in Tyrosine Kinase Inhibitors Treatments for Chronic Myeloid Leukemia: A Review
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm driven by a fusion gene, encoding for the chimeric protein BCR-ABL, with constitutive tyrosine kinase activity. The use of tyrosine kinase inhibitors (TKIs) has drastically improved survival, but there are significant concerns about car...
Autores principales: | Santoro, Marco, Mancuso, Salvatrice, Accurso, Vincenzo, Di Lisi, Daniela, Novo, Giuseppina, Siragusa, Sergio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287514/ https://www.ncbi.nlm.nih.gov/pubmed/34290617 http://dx.doi.org/10.3389/fphys.2021.675811 |
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