Growth and Antioxidant-Related Effects of the Reestablished Ascorbic Acid Pathway in Zebrafish (Danio rerio) by Genomic Integration of L-Gulonolactone Oxidase From Cloudy Catshark (Scyliorhinus torazame)

Loss of L-gulonolactone oxidase (GULO), which catalyzes the last step of the ascorbic acid (AA) biosynthesis pathway, results in a complete lack of AA in several Osteichthyes fish species, including zebrafish. In this study, sGULO, the active GULO gene from cloudy catshark (Scyliorhinus torazame) wa...

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Detalles Bibliográficos
Autores principales: Shanaka, K. A. S. N., Jung, Sumi, Janson, N. D., Jayasingha, J. R. P., Madushani, K. P., Kim, Myoung-Jin, Lee, Jehee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287572/
https://www.ncbi.nlm.nih.gov/pubmed/34290620
http://dx.doi.org/10.3389/fphys.2021.685595

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