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Simplified treatment algorithm for the management of trauma-induced hemorrhage without viscoelastic testing

Uncontrolled bleeding after major trauma remains a significant cause of death, with up to a third of trauma patients presenting with signs of coagulopathy at hospital admission. Rapid correction of coagulopathy is therefore vital to improve mortality rates and patient outcomes in this population. Ea...

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Detalles Bibliográficos
Autor principal: Casu, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287615/
https://www.ncbi.nlm.nih.gov/pubmed/34337159
http://dx.doi.org/10.1136/tsaco-2021-000779
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author Casu, Sebastian
author_facet Casu, Sebastian
author_sort Casu, Sebastian
collection PubMed
description Uncontrolled bleeding after major trauma remains a significant cause of death, with up to a third of trauma patients presenting with signs of coagulopathy at hospital admission. Rapid correction of coagulopathy is therefore vital to improve mortality rates and patient outcomes in this population. Early and repeated monitoring of coagulation parameters followed by clear protocols to correct hemostasis is the recommended standard of care for bleeding trauma patients. However, although a number of treatment algorithms are available, these are frequently complex and can rely on the use of viscoelastic testing, which is not available in all treatment centers. We therefore set out to develop a concise and pragmatic algorithm to guide treatment of bleeding trauma patients without the use of point-of-care viscoelastic testing. The algorithm we present here is based on published guidelines and research, includes recommendations regarding treatment and dosing, and is simple and clear enough for even an inexperienced physician to follow. In this way, we have demonstrated that treatment protocols can be developed and adapted to the resources available, to offer clear and relevant guidance to the entire trauma team.
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spelling pubmed-82876152021-07-30 Simplified treatment algorithm for the management of trauma-induced hemorrhage without viscoelastic testing Casu, Sebastian Trauma Surg Acute Care Open Current Opinion Uncontrolled bleeding after major trauma remains a significant cause of death, with up to a third of trauma patients presenting with signs of coagulopathy at hospital admission. Rapid correction of coagulopathy is therefore vital to improve mortality rates and patient outcomes in this population. Early and repeated monitoring of coagulation parameters followed by clear protocols to correct hemostasis is the recommended standard of care for bleeding trauma patients. However, although a number of treatment algorithms are available, these are frequently complex and can rely on the use of viscoelastic testing, which is not available in all treatment centers. We therefore set out to develop a concise and pragmatic algorithm to guide treatment of bleeding trauma patients without the use of point-of-care viscoelastic testing. The algorithm we present here is based on published guidelines and research, includes recommendations regarding treatment and dosing, and is simple and clear enough for even an inexperienced physician to follow. In this way, we have demonstrated that treatment protocols can be developed and adapted to the resources available, to offer clear and relevant guidance to the entire trauma team. BMJ Publishing Group 2021-07-16 /pmc/articles/PMC8287615/ /pubmed/34337159 http://dx.doi.org/10.1136/tsaco-2021-000779 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Current Opinion
Casu, Sebastian
Simplified treatment algorithm for the management of trauma-induced hemorrhage without viscoelastic testing
title Simplified treatment algorithm for the management of trauma-induced hemorrhage without viscoelastic testing
title_full Simplified treatment algorithm for the management of trauma-induced hemorrhage without viscoelastic testing
title_fullStr Simplified treatment algorithm for the management of trauma-induced hemorrhage without viscoelastic testing
title_full_unstemmed Simplified treatment algorithm for the management of trauma-induced hemorrhage without viscoelastic testing
title_short Simplified treatment algorithm for the management of trauma-induced hemorrhage without viscoelastic testing
title_sort simplified treatment algorithm for the management of trauma-induced hemorrhage without viscoelastic testing
topic Current Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287615/
https://www.ncbi.nlm.nih.gov/pubmed/34337159
http://dx.doi.org/10.1136/tsaco-2021-000779
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