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Efficacy and Safety of Axicabtagene Ciloleucel and Tisagenlecleucel Administration in Lymphoma Patients With Secondary CNS Involvement: A Systematic Review

BACKGROUND: The efficacy and safety of chimeric antigen receptor T (CAR-T) cell therapy in the treatment of non-Hodgkin’s lymphoma has already been demonstrated. However, patients with a history of/active secondary central nervous system (CNS) lymphoma were excluded from the licensing trials conduct...

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Detalles Bibliográficos
Autores principales: Wu, XiaoQin, Zhang, XinYue, Xun, RenDe, Liu, MengSi, Sun, Zhen, Huang, JianChao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287648/
https://www.ncbi.nlm.nih.gov/pubmed/34290712
http://dx.doi.org/10.3389/fimmu.2021.693200