Cargando…

Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins

Early and persistent activation of complement is considered to play a key role in the pathogenesis of COVID-19. Complement activation products orchestrate a proinflammatory environment that might be critical for the induction and maintenance of a severe inflammatory response to SARS-CoV-2 by recruit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ali, Youssif M., Ferrari, Matteo, Lynch, Nicholas J., Yaseen, Sadam, Dudler, Thomas, Gragerov, Sasha, Demopulos, Gregory, Heeney, Jonathan L., Schwaeble, Wilhelm J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287855/ https://www.ncbi.nlm.nih.gov/pubmed/34290717 http://dx.doi.org/10.3389/fimmu.2021.714511

Ejemplares similares

Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice
por: Ali, Youssif M., et al.
Publicado: (2023)

Secondary Complement Deficiency Impairs Anti-Microbial Immunity to Klebsiella pneumoniae and Staphylococcus aureus During Severe Acute COVID-19
por: Ali, Youssif M., et al.
Publicado: (2022)

Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury
por: Alghadban, Samy, et al.
Publicado: (2019)

Inhibition of the lectin pathway of complement ameliorates hypocomplementemia and restores serum bactericidal activity in patients with severe COVID‐19
por: Lynch, Nicholas J., et al.
Publicado: (2022)

Development and characterization of narsoplimab, a selective MASP-2 inhibitor, for the treatment of lectin-pathway–mediated disorders
por: Dudler, Thomas, et al.
Publicado: (2023)

The Lectin Pathway of Complement Activation Is a Critical Component of the Innate Immune Response to Pneumococcal Infection
por: Ali, Youssif M., et al.
Publicado: (2012)

Human L-ficolin, a Recognition Molecule of the Lectin Activation Pathway of Complement, Activates Complement by Binding to Pneumolysin, the Major Toxin of Streptococcus pneumoniae
por: Ali, Youssif M., et al.
Publicado: (2013)

Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1
por: Orsini, Franca, et al.
Publicado: (2016)

Role of the lectin pathway of complement in hematopoietic stem cell transplantation-associated endothelial injury and thrombotic microangiopathy
por: Gavriilaki, Eleni, et al.
Publicado: (2021)

Does the Lectin Complement Pathway Link Kawasaki Disease and SARS-CoV-2?
por: Polycarpou, Anastasia, et al.
Publicado: (2021)

Which pathways trigger the role of complement in ischaemia/reperfusion injury?
por: Farrar, Conrad A., et al.
Publicado: (2012)

Complementary Roles of the Classical and Lectin Complement Pathways in the Defense against Aspergillus fumigatus
por: Rosbjerg, Anne, et al.
Publicado: (2016)

Lectin Pathway of Complement Activation Is Associated with Vulnerability of Atherosclerotic Plaques
por: Fumagalli, Stefano, et al.
Publicado: (2017)

The Influence of the Lectin Pathway of Complement Activation on Infections of the Respiratory System
por: Świerzko, Anna S., et al.
Publicado: (2020)

Distinct Roles of Classical and Lectin Pathways of Complement in Preeclamptic Placentae
por: Belmonte, Beatrice, et al.
Publicado: (2022)

Plasma Lectin Pathway Complement Proteins in Patients With COVID-19 and Renal Disease
por: Medjeral-Thomas, Nicholas R., et al.
Publicado: (2021)

Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases
por: Castillo-Olivares, Javier, et al.
Publicado: (2021)

Be on Target: Strategies of Targeting Alternative and Lectin Pathway Components in Complement-Mediated Diseases
por: Dobó, József, et al.
Publicado: (2018)

The Lectin Complement Pathway Is Involved in Protection Against Enteroaggregative Escherichia coli Infection
por: Adler Sørensen, Camilla, et al.
Publicado: (2018)

Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19
por: Niederreiter, Janina, et al.
Publicado: (2022)

Targeted deletions of complement lectin pathway genes improve outcome in traumatic brain injury, with MASP-2 playing a major role
por: Mercurio, D., et al.
Publicado: (2020)

The salivary scavenger and agglutinin binds MBL and regulates the lectin pathway of complement in solution and on surfaces
por: Reichhardt, Martin P., et al.
Publicado: (2012)

Complement Alternative and Mannose-Binding Lectin Pathway Activation Is Associated With COVID-19 Mortality
por: Defendi, Federica, et al.
Publicado: (2021)

Corrigendum: Complement activation via the lectin and alternative pathway in patients with severe COVID-19
por: Niederreiter, Janina, et al.
Publicado: (2023)

Ficolin-2 Lectin Complement Pathway Mediates Capsule-Specific Innate Immunity Against Invasive Pneumococcal Disease
por: Nahm, Moon H., et al.
Publicado: (2022)

Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism
por: Oroszlán, Gábor, et al.
Publicado: (2017)

The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?
por: Poppelaars, Felix, et al.
Publicado: (2021)

The role of the lectin pathway of the complement system in SARS-CoV-2 lung injury
por: Malaquias, Mineia Alessandra Scaranello, et al.
Publicado: (2021)

Complement lectin pathway activation is associated with COVID-19 disease severity, independent of MBL2 genotype subgroups
por: Hurler, Lisa, et al.
Publicado: (2023)

The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation
por: Kusakari, Kohei, et al.
Publicado: (2022)

Thrombotic microangiopathy mediates poor prognosis among lupus nephritis via complement lectin and alternative pathway activation
por: Zhang, Binshan, et al.
Publicado: (2022)

SARS-CoV-2 Antibodies Mediate Complement and Cellular Driven Inflammation
por: Jarlhelt, Ida, et al.
Publicado: (2021)

Cardioprotection by an anti-MASP-2 antibody in a murine model of myocardial infarction
por: Clark, James, E, et al.
Publicado: (2018)

Local and Systemic Concentrations of Pattern Recognition Receptors of the Lectin Pathway of Complement in a Cohort of Patients With Interstitial Lung Diseases
por: Vogt, Severin, et al.
Publicado: (2020)

Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D
por: Holers, V. Michael, et al.
Publicado: (2020)

Complement Overactivation and Consumption Predicts In-Hospital Mortality in SARS-CoV-2 Infection
por: Sinkovits, György, et al.
Publicado: (2021)

Hepatitis B Virus Infection Among Leprosy Patients: A Case for Polymorphisms Compromising Activation of the Lectin Pathway and Complement Receptors
por: Boldt, Angelica Beate Winter, et al.
Publicado: (2021)

Complement lectin pathway components MBL and MASP-1 promote haemostasis upon vessel injury in a microvascular bleeding model
por: Golomingi, Murielle, et al.
Publicado: (2022)

MAp34 Regulates the Non-specific Cell Immunity of Monocytes/Macrophages and Inhibits the Lectin Pathway of Complement Activation in a Teleost Fish
por: Mu, Liangliang, et al.
Publicado: (2020)

SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems
por: Savitt, Anne G., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_o9im2o9b76um16rf466v87p9nr