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S1P(2)-Gα(12) Signaling Controls Astrocytic Glutamate Uptake and Mitochondrial Oxygen Consumption

Glutamate is the principal excitatory neurotransmitter in the human brain. Following neurotransmission, astrocytes remove excess extracellular glutamate to prevent neurotoxicity. Glutamate neurotoxicity has been reported in multiple neurologic diseases including multiple sclerosis (MS), representing...

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Detalles Bibliográficos
Autores principales:	Jonnalagadda, Deepa, Kihara, Yasuyuki, Rivera, Richard, Chun, Jerold
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2021
Materias:	Research Article: New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287876/ https://www.ncbi.nlm.nih.gov/pubmed/33893167 http://dx.doi.org/10.1523/ENEURO.0040-21.2021

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