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Transcription factor RFX7 governs a tumor suppressor network in response to p53 and stress

Despite its prominence, the mechanisms through which the tumor suppressor p53 regulates most genes remain unclear. Recently, the regulatory factor X 7 (RFX7) emerged as a suppressor of lymphoid neoplasms, but its regulation and target genes mediating tumor suppression remain unknown. Here, we identi...

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Detalles Bibliográficos
Autores principales: Coronel, Luis, Riege, Konstantin, Schwab, Katjana, Förste, Silke, Häckes, David, Semerau, Lena, Bernhart, Stephan H, Siebert, Reiner, Hoffmann, Steve, Fischer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287911/
https://www.ncbi.nlm.nih.gov/pubmed/34197623
http://dx.doi.org/10.1093/nar/gkab575